High-yield cell and molecular biology
著者
書誌事項
High-yield cell and molecular biology
（High-yield series）
Lippincott Williams & Wilkins, c1999
- : pbk
大学図書館所蔵 件 / 全6件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references
内容説明・目次
内容説明
"High-Yield Cell and Molecular Biology" gives you more of what you need to prepare you for the USMLE Step 1! The information found in this text provides a strong understanding of introductory undergraduate cell and molecular biology which serves as a valuable review resource for the board exam. As part of the "High-Yield" series, material is presented in a concise, uncluttered fashion. The sections cover information typically found in a second year molecular biology course such as chromosomal DNA, chromosome replication and DNA synthesis, molecular genetics, gene amplification, inherited diseases and molecular immunology. Well illustrated, this text provides students with a strong foundation to prepare them for more advanced work in cell and molecular biology. It also serves as a great source for course review.
目次
- Part 1 Packaging of chromosomal DNA: nucleic acids
- the human genome
- chromosomes
- genes
- chromatin. Part 2 Chromosome replication and DNA synthesis: replication fork
- telomere
- damage and repair of DNA
- clinical importance of DNA repair mechanisms. Part 3 Genetic recombination: general recombination
- site-specific recombination. Part 4 Transposable elements: mechanisms of transposition
- transposable elements and genetic variability. Part 5 Gene amplification: clinical considerations. Part 6 Recombinant DNA technology: restriction enzymes
- gel electrophoresis
- enzymatic method of DNA sequencing
- southern blotting and prenatal testing for sickle cell anaemia
- isolating a human gene with DNA cloning
- polymerase chain reaction (PCR)
- producing a protein from a cloned gene
- site-directed mutagenesis and transgenic animals. Part 7 Control of gene expression: mechanism of gene regulation
- structure of transcription factors and gene regulatory proteins
- clinical consideration - growth hormone deficiency and Pit-1 transcription factor
- the "lac" operon
- summary. Part 8 Protein synthesis: transcription
- converting an RNA transcription to mRNA
- translation
- clinical considerations. Part 9 The nucleolus
- organization of the nucleolus
- assembly of the ribosome
- ultrastructure of the nucleolus. Part 10 Mutations of the DNA sequence: silent mutations
- missense mutations
- nonsense mutations
- frameshift mutations
- translocation mutations
- RNA splicing mutations
- transposable element mutations
- trinucleotide repeat mutations. Part 11 Molecular genetics: polymorphisms
- linkage (coinheritance)
- population genetics. Part 12 Inherited diseases: autosomal dominant inheritance
- autosomal recessive inheritance
- x-linked recessive inheritance
- mitochondrial inheritance
- multifactorial inheritance
- table of inherited disorders. Part 13 Multifactorial inherited diseases: definition
- example - type 1 diabetes. Part 14 Proto-oncogenes, oncogenes and anti-oncogenes: definitions
- designations
- classification of oncogenes
- mechanism of action of the "ras" proto-oncogene
- anti-oncogenes (tumor-suppressor genes)
- molecular pathology of colorectal cancer. Part 15 The cell cycle: phases of the cell cycle
- control of the cell cycle
- stages of the M phase. Part 16 Homeotic genes and anterior-posterior body pattern formation: human homeotic genes. Part 17 Mitochondrial genes: gene products that are encoded by mitochondrial DNA (mrDNA)
- other mitochondrial proteins
- mitochondrial diseases. Part 18 Molecular immunology: the clonal selection theory
- the B lymphocyte (B cell)
- the T lymphocyte (T cell)
- clinical considerations. Part 19 Receptors and signal transduction: ion channel-linked receptors
- G-protein-linked receptors
- enzyme-linked receptors
- steroid hormone (intracellular) receptors
- receptor types
- nitric oxide (NO)
- receptor-mediated endocytosis.
「Nielsen BookData」 より
