Pharmacogenomics

Author(s)

Bibliographic Information

Pharmacogenomics

edited by Werner Kalow, Urs A. Meyer, Rachel F. Tyndale

(Drugs and the pharmaceutical sciences, v. 113)

M. Dekker, Inc., c2001

Available at  / 10 libraries

Search this Book/Journal

Note

Includes bibliographical references and index

Description and Table of Contents

Description

"Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."

Table of Contents

  • Historical aspects of pharmacogenomics
  • pharmacogenomics, biomarkers and the promise of personalized medicine
  • current status - pharmacogenetics/drug metabolism
  • pharmacogenetics -receptors
  • pharmacogenetics of drug transporters
  • interethnic differences in drug response
  • pharmacogenetics - clinical viewpoints
  • tools of the trade - the technologies and challenges of pharmacogenetics
  • molecular diagnostics and development of biotechnology-based diagnostics
  • technologies for the analysis of single-nucleotide polymorphisms - an overview
  • multiplex fluorescent minisequencing applied to the typing of genes encoding drug-metabolizing enzymes
  • multiplex genotyping by specialized mass spectrometry
  • serial analysis of gene expression -transcriptional insights into functional biology
  • proteomics
  • bioinformatics - WWW resources
  • applied bioinformatics
  • mapping of disease loci
  • positional cloning and disease gene identification
  • general conclusions and future directions.

by "Nielsen BookData"

Related Books: 1-1 of 1

Details

  • NCID
    BA5268821X
  • ISBN
    • 0824705440
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    New York
  • Pages/Volumes
    xi, 403 p.
  • Size
    24 cm
  • Parent Bibliography ID
Page Top