Antioxidants in diabetes management

著者

• Packer, Lester

書誌事項

Antioxidants in diabetes management

edited by Lester Packer ... [et al.]

（Oxidative stress and disease / series editors, Lester Packer, Enrique Cadenas）

M. Dekker, c2000

注記

"UNESCO-MCBN, Global Network of Molecular & Cell Biology, Oxygen Club of California, '98 World Congress Sponsored Workshop"--T.p.

Includes bibliographical references and index

内容説明・目次

内容説明

This volume summarizes current understanding of the pathogenic role of oxidative stress in the onset and progression of diabetes and its complications, and presents results of studies aimed at regulating oxidatively induced complications through the use of antioxidants. Examines the presence of impaired microcirculation, capillary hypoxia, and ischemia syndrome in diabetic complications! Designed to stimulate scientific discussion and curiosity about the causes of diabetes, with contributions from nearly 65 clinicians and researchers who cite more than 1300 sources, Antioxidants in Diabetes Management focuses on stringent control of hyperglycemia to prevent or modify onset and progression promotes the development of intervention strategies because of the therapeutic limitations of hypoglycemic therapy emphasizes the potential synergistic effects of an interlinked antioxidant network investigates the controversy surrounding the significance of oxidative stress markers in diabetes highlights oxidative stress and antioxidant treatment in animal models for juvenile and adult onset diabetes explores the hypothesis that ischemic reperfusion is the primary cause of diabetic polyneuropathy links protein kinase C activation to the development of diabetic vascular complications and the effectiveness of vitamin E in preventing these abnormalities spotlights recent clinical trials of therapeutic effects of antioxidants to reduce insulin resistance and much more! Illustrating the therapeutic potential of antioxidants for the treatment of diabetes, Antioxidants in Diabetes Management is an unparalleled reference for endocrinologists, nutritionists and dietitians, cell biologists and biochemists, cardiologists, pathologists, and graduate and medical school students in these disciplines.

目次

Oxidative Stress and Antioxidants: The Antioxidant Network, -Lipoic Acid, and Diabetes Lester Packer Oxidative Stress in Diabetes: Why Does Hyperglycemia Induce the Formation of Reactive Oxygen Species? Peter Roesen, Xue Liang Du, and Guang-Zhi Sui Oxidative Stress Markers in Human Disease: Application to Diabetes and to Evaluation of the Effects of Antioxidants Barry Halliwell Plasma Lipid Hydroperoxide and Vitamin E Profiles in Patients with Diabetes Mellitus Jaffar Nourooz-Zadeh Concentrations of Antioxidative Vitamins in Plasma and LDL of Diabetic Patients Wolfgang Leonhardt Oxidative Stress in Diabetes John W. Baynes and Suzanne R. Thorpe Antioxidative Defense in Diabetic Peripheral Nerve: Effects of DL- -Lipoic Acid, Aldose Reductase Inhibitor and Sorbitol Dehydrogenase Inhibitor Irina G. Obrosova, Douglas A. Greene, and Hans-Jochen Lang Pathways of Glucose-Mediated Oxidative Stress in Diabetic Neuropathy Douglas A. Greene, Irina G. Obrosova, Martin J. Stevens, and Eva L. Feldman Experimental Diabetic Neuropathy: Oxidative Stress and Antioxidant Therapy Hans J. Tritschler, James D. Schmelzer, Yutaka Kishi, Yoshiyuki Mitsui, Masaaki Nagamatsu, Kim K. Nickander, Paula J. Zollman, and Phillip A. Low Antioxidants in the Treatment of Diabetic Polyneuropathy: Synergy with Essential Fatty Acids Norman E. Cameron and Mary A. Cotter A Thioctic Acid-Gamma-Linolenic Acid Conjugate Protects Neurotrophic Support in Experimental Diabetic Neuropathy Luke Hounsom and David R. Tomlinson Clinical Trials of -Lipoic Acid in Diabetic Polyneuropathy and Cardiac Autonomic Neuropathy Dan Ziegler Oxidative Stress, NF-kB Activation, and Late Diabetic Complications Peter P. Nawroth, Valentin Borcea, Angelika Bierhaus, Martina Joswig, Stephan Schiekofer, and Hans J. Tritschler Molecular Basis of -Tocopherol Action and Its Protective Role Against Diabetic Complications Angelo Azzi, Roberta Ricciarelli, Sophie Clement, and Nesrin OEzer Protein Kinase C Activation, the Development of Diabetic Vascular Complications, and the Role of Vitamin E in Preventing These Abnormalities Sven-Erik Bursell and George L. King Oxidative Stress and Pancreatic -Cell Destruction in Insulin-Dependent Diabetes Mellitus Mizuo Hotta, Eiji Yamato, and Jun-ichi Miyazaki Interrelationship Between Oxidative Stress and Insulin Resistance Karen Yaworsky, Romel Somwar, and Amira Klip Oxidative Stress and Antixodant Treatment: Effects on Muscle Glucose Transport in Animal Models of Type 1 and Type 2 Diabetes Erik J. Henriksen Oxidative Stress and Insulin Action: A Role for Antioxidants? Stephan Jacob, Rainer Lehmann, Kristian Rett, and Hans Ulrich-Haring

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA52755226
• ISBN:
  • 0824788443
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xxi, 349 p.
• 大きさ: 24 cm
• 親書誌ID:
  • BA42881133