The IACUC handbook

著者

    • Silverman, Jerald
    • Suckow, Mark A.
    • Murthy, Sreekant
    • National Institutes of Health (U.S.). Institutional Animal Care and Use Committee

書誌事項

The IACUC handbook

edited by Jerald Silverman, Mark A. Suckow, Sreekant Murthy

CRC Press, c2000

  • : alk. paper

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee has evolved as the premier instrument of animal welfare oversight within research institutions in the U.S. Its mission, in part, is to ensure that investigators, research technicians, animal care personnel and others are adequately trained to conduct research with animals in a proper and humane manner. But equally important is that the IACUC itself be adequately trained with regard to the successful interpretation and implementation of regulations and guidelines for proper animal care and use. The IACUC Handbook focuses on both basic and advanced concerns of those who participate in activities of Institutional Animal Care and Use Committees. Exhaustive in its content and written by leading authorities in the field, this handbook addresses those questions and problems that often confront IACUCs, and gives accurate, succinct answers. Information is provided in "Question and Answer" format, with the authors offering their personal opinions against a background of regulatory information. Under the "regulatory " heading, pertinent sections from such sources as the Animal Welfare Act and its regulations, the Health Research Extension Act of 1985, the Public Health Service Policy on Humane Care and Use of Laboratory Animals, the Guide for the Care and Use of Laboratory Animals, and others are included. The handbook also provides the personal opinions of chapter authors and results from informal surveys as examples of the approaches institutions have taken to solve complex issues. While not scientific, the surveys provide the reader with additional opinions. With the role and impact of the Institutional Animal Care and Use Committee expected to grow in scope and complexity, The IACUC Handbook provides a foundation for those attempting to understand and implement the many and varied responsibilities of this committee.

目次

Abbreviations Used in This Book Preface Introduction - Nelson Garnett, D.V.M., and W. Ron DeHaven, D.V.M. Origins of the IACUC - Harry Rozmiarek, D.V.M., Ph.D. Circumstances Requiring an IACUC - Richard C. VanSluyters, O.D., Ph.D., Jane E. Simpson, and Ralph B. Dell, M.D. Creation of an IACUC - Richard C. Van Sluyters, O.D., Ph.D., Jane E. Simpson, and Ralph B. Dell, M.D. Reporting Lines of the IACUC - Richard C. Van Sluyters, O.D., Ph.D., Jane E. Simpson, and Ralph B. Dell, M.D. General Composition of the IACUC and Specific Roles of the IACUC Members - Christian E. Newcomer, V.M.D., M.S. Frequency and Conduct of Regular IACUC Meetings - Sreekant Murthy, Ph.D. General Format of IACUC Protocol Forms - Christian E. Newcomer, V.M.D., M.S. Submission and Maintenance of IACUC Protocols - Farol N. Tomson, D.V.M., M.B.A. General Concepts of Protocol Review - Ernest D. Prentice, Ph.D., and Gwenn S.F. Oki, M.P.H. Amending IACUC Protocols - Diane J. Gaertner, D.V.M., and Kathleen D. Moody, V.M.D., M.S. Continuing Review of Protocols - Ernest D. Prentice, Ph.D. Justification for the Use of Animals - Joseph S. Spinelli, D.V.M. Justification of the Number of Animals to Be Used - Edward J. Gracely, Ph.D. Animal Acquisition and Disposition - Michael J. Huerkamp, D.V.M., and David R. Archer, Ph.D. Animal Housing and Use Sites - Cynthia Gillett, D.V.M. Pain and Distress - Paul Flecknell, M.A., Vet. M.B., Ph.D., and Jerald Silverman, D.V.M., M.P.S. Euthanasia - Peggy J. Danneman, V.M.D., M.S. Surgery - Elizabeth J. Dawe, D.V.M. Antigens, Antibodies and Blood Collection - Harold F. Stills, Jr., D.V.M. Occupational Health and Safety - Stefan Wagener, Ph.D., and Susan Stein, D.V.M., M.S. Personnel Training - Howard G. Rush, D.V.M. Academic Freedom and Proprietary Information - Sallie Thieme Sanford, J.D., and Lisa A. Vincler, J.D. General Concepts of the Facility Inspection and Program Review - Stephen K. Curtis, D.V.M. Inspection of Animal Housing Areas - Patricia A. Ward, B.S., M.P.A. Inspection of Individual Laboratories - Neil S. Lipman, V.M.D., and Scott E. Perkins, V.M.D., M.P.H. Inspection of Surgery Areas - Scott E. Perkins, V.M.D., M.P.H., and Neil S. Lipman, V.M.D. Assessment of Veterinary Care - Mark A. Suckow, D.V.M., and Bernard J. Doerning, D.V.M. Laboratory Animal Enrichment - Kathryn A.L. Bayne, M.S., D.V.M., Ph.D. Animal Mistreatment and Protocol Noncompliance - Jerald Silverman, D.V.M., M.P.S. Appendix A: Animal Welfare Act Appendix B: Animal Welfare Act Regulations Appendix C: Health Research Extension Act of 1985 Appendix D: Public Health Service Policy on Humane Care and Use of Laboratory Animals Appendix E: U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training Index

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