Dialysis, dialyzers and sorbents : where are we going?
Author(s)
Bibliographic Information
Dialysis, dialyzers and sorbents : where are we going?
（Contributions to nephrology, v. 133）
Karger, c2001
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Note
Includes bibliographical references and indexes
Description and Table of Contents
Description
Over the last decade, the availability of new devices and membranes has led to the development of modern hemodialysis techniques in which clinical tolerance and efficiency have significantly improved patient morbidity and mortality. Nevertheless, there are still limitations imposed by hemodialysis, manifested by the long-term complications occurring in patients treated for several years. Since most of these complications seem to be related to the chronic inflammation of ESRD patients and the progressive accumulation of middle-large molecules such as beta-2-microglobulin, GIP, leptin and others, a novel approach is needed, capable of adequately removing these substances from the body of the patient. New polymers with a biocompatible surface and high affinity for specific molecules have already been introduced to the market, and adsorption might in fact represent a new form of solute removal. Featuring articles by renowned experts, this volume provides the reader with a comprehensive summary of the most updated technology in the field of hemodialysis. New devices and techniques are described and discussed in detail, complemented by preliminary results; the rationale for adsorptive therapies completes the analysis. Residents and fellows, as well as staff physicians and members of the academic and scientific community involved in practice and research in the field of hemodialysis will find this book a valuable addition to their bookshelves.
Table of Contents
- Unmet clinical needs in dialysis - what can we do?
- new technologies for patients with end-stage renal disease - the US regulatory perspective
- the role of middle molecules in uremia - preliminary report of an international survey of nephrologists and scientists
- are new toxins appearing on the horizon?
- redesigning the map of uremic toxins
- reactive carbonyl compounds as uremic toxins
- haemodialysis membranes - a matter of fact or taste?
- new developments in hemodialyzers
- computerized selection of membranes and hemodialysers
- history of sorbents in uremia
- adsorption techniques and the use of sorbents
- characterization of flow-dynamic pattern in a new sorbent cartridge for combined hemoperfusion-hemodialysis
- first clinical experience with an adjunctive hemoperfusion device designed specifically to remove 2-Microglobulin in hemodialysis
- rationale for combined hemoperfusion/hemodialysis in uremia
- use of sorbents in acute renal failure and sepsis.
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