New antibacterial strategies : proceedings of an international symposium sponsored by Glaxo Research, Brocket Hall, Hertfordshire, 30 June-3 July 1990

Bibliographic Information

New antibacterial strategies : proceedings of an international symposium sponsored by Glaxo Research, Brocket Hall, Hertfordshire, 30 June-3 July 1990

edited by Harold C. Neu ; organizing committee, K.P.W.J. McAdam ... [et al.]

(Frontiers of infectious diseases)

Churchill Livingstone, 1990

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Note

Includes bibliographical referneces and index

Description and Table of Contents

Description

In this series, scientists review the major issues involved in bacterial infections. This title covers Borrelia burgdoferi infections, areas for vaccine use such as diarrhoeal disease, urinary tract infections and other infections of mucosal surfaces. It offers information relevant to clincians and health care professionals worldwide, as well as basic scientists. It also examines the future of interleukins and colony stimulating factors in treatment of bacterial infections.

Table of Contents

  • Part 1 Plenary lecture I Bacterial diseases - unsolved problems: Borrelia - the epidemiology of Borrelia burgdorferi infections, Lyme borreliosis - host-parasite interactions, vaccine and antimicrobials, immunodominant proteins of Borrelia burgdorferi - implications for improving serodiagnosis of Lyme borreliosis
  • vaccines - polysaccharide vaccines - vaccines needed for the 1990s, Salmonella vaccines
  • mucosal surface infections - the role of bacterial adherence in urinary tract infections, the pathogenesis of diarrhoea caused by Escherichia coli, pathogenesis of Heliobacter pylori-induced gastroduodenal diseases
  • resistance - the molecular basis of B-lactamase induction in enterobacteria, the molecular basis of quinolone action and resistance, transport systms and their role in drug resistance in bacteria and mammalian cells. Part 2 Plenary lecture II Leprosy - a paradigm for host-microbe interactions: intracellular mechanisms - the intracellular pharmcokinetics and activity of antibiotics, microbial heat-shock protein and autoimmune disease
  • immunomodulatorsm - interleukins and their use as therapeutic agents, the roles of colony-stimulating factors in the treatment of infections.

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