Clinical pharmacology of local anesthetics

Author(s)

    • Tetzlaff, John E.

Bibliographic Information

Clinical pharmacology of local anesthetics

John E. Tetzlaff

Butterworth-Heinemann, c2000

Available at  / 2 libraries

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Note

Includes bibliographies and index

Description and Table of Contents

Description

Anesthesiologists need to understand the drug's action, its reaction to other drugs being administered, its reaction to a concomitant condition of the patient, and how the drug pertains to certain regional anesthesia procedures. This vital information is addressed in "Clinical Pharmacology of Local Anesthetics", in addition to material on a drug's time of onset, potency, duration, and toxicity. The overall strategy of interruption of pain signals in the acute setting is discussed as well as the experimental evidence for preemptive analgesia.

Table of Contents

  • Physiology of Excitable Cells
  • Organic Chemistry of a Local Anesthetic Molecule
  • Physiology of Conduction Blockade
  • Disposition of Local Anesthetics after They Are Injected
  • Central Nervous System Toxicity
  • Cardiac Toxicity
  • Allergy to Local Anesthetics
  • Procaine
  • Chloroprocaine
  • Tetracaine
  • Cocaine
  • Benzocaine
  • Lidocaine
  • Mepivacaine
  • Prilocaine
  • Etidocaine
  • Bupivacaine
  • Ropivacaine
  • Dibucaine
  • Chemical Alteration of Local Anesthetic Solutions to Increase the Speed of Onset of Conduction Block-Dextran Carbonation and Alkalinization
  • Addition of Vasoconstrictors
  • Tetracaine, Adrenaline, Cocaine
  • Eutectic Mixture of Local Anesthetics
  • Compounding of Local Anesthetics
  • Use of Local Anesthetic for Ambulatory Anesthesia
  • Use of Local Anesthetics in Cardiothoracic Anesthesia
  • Use of Local Anesthetics for Dentistry and Oral Surgery
  • Use of Local Anesthetics in Ear, Nose and Throat Surgery
  • Use of Local Anesthetics for General Surgery
  • Use of Local Anesthetic with Gynecologic Surgery
  • Local Anesthetics and Neurosurgery
  • Use of Local Anesthetics in Obstetrics
  • Use of Local Anesthetic for Ophthalmology
  • Use of Local Anesthetics for Orthopedic Surgery
  • Local Anesthesia and Pediatric Patients
  • Use of Local Anesthetics for Plastic and Dermatologic Surgery
  • Use of Local Anesthetics for Urologic Surgery Patients
  • Use of Local Anesthetics for Vascular Surgery

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