Reactive oxygen metabolites : chemistry and medical consequences
著者
書誌事項
Reactive oxygen metabolites : chemistry and medical consequences
CRC Press, c2001
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注記
Includes bibliographical references (399-527) and indexes
内容説明・目次
内容説明
In recent years, the field of radical chemistry has undergone explosive growth. Although its roots lie in organic chemistry, the implications of its findings are having enormous impact in a broad range of disciplines, and we now have evidence for radical involvement in over 100 diseases. As important as this is, however, the subject of radicals and reactive oxygen metabolites (ROMs) is complex and barely touched upon in the curriculum of medical schools.
Reactive Oxygen Metabolites brings the subject within the grasp of even those with little preparation in chemistry. From the basic chemistry of radicals through the pathology, the author provides a clear and thorough introduction to ROMs and their importance to human health and disease. Exhaustively researched and referenced, this highly readable work will give you the ability to critically analyze and evaluate many pathological problems arising from the chemistry of ROMs and reduce them to their lowest common denominator. It is the ideal vehicle for people who need to understand the importance of reactive oxygen and nitrogen species in human health and disease but have neither the time, the inclination, nor perhaps the background to work their way through the mountain of original literature.
目次
The Pros and Cons of Living in an Oxygen Atmosphere. Basic Chemistry of Radicals. Chemistry of Oxygen-Derived Radicals. Chemistry of Electronically Excited States. Formation of Reactive Oxygen Metabolites in Vivo. Reactions of Reactive Oxygen Metabolites with Important Biomolecules. Nitric Oxide. Antioxidants. Pathological Processes Involving Reactive Oxygen Metabolites. Conclusion. References.
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