In search of madness : schizophrenia and neuroscience
著者
書誌事項
In search of madness : schizophrenia and neuroscience
Oxford University Press, 2001
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内容説明・目次
内容説明
Is definitive understanding of schizophrenia as a brain disease just around the corner? This book synthesizes twenty years of research into diverse fields such as the symptoms, biology, and neurochemistry of schizophrenia, exploring theories of the disease and possibilities for future research. In fact, it seems that schizophrenia patients differ from healthy people more in their cognition than in their biology, an understanding of which will revolutionize both
neuroscience and psychiatry.
目次
1: Illness and Evidence
The Science of Schizophrenia
Rules of Evidence
Conclusion
2: The Nature of Symptoms
Psychiatric Pioneers
Symptoms and Diagnosis
The Mind of Madness
The Delusional World
Counterfeit Experience
Crazy Thoughts
General Summary and Conclusions
3: The Mark of Madness
Candidate Markers of Schizophrenia
Traits and States
Specificity
Marking Genes
Conclusions
4: Executive Incompetence
The Search for the Schizophrenic Lesion
The Frontal Brain and Its Mind
Schizophrenia and the Frontal Mind
Pictures of the Brain
The Frontal-Executive Brain and its Contribution to Schizophrenia
5: The Biology of Meaning
The Temporal Lobe and its Semantic Functions
Schizophrenia and the Semantic Brain
Neurobiology of the Temporal Lobe in Schizophrenia
The Temporal-Semantic Brain and its Contribution to Schizophrenia
6: Neurochemical Tempest
Dopamine: Modulator of Mind and Movement
Serotonin: Chemical of Sleep and Moods
Glutamate: The Brain's Workhorse
General Summary and Conclusions
7: The Strangeness of Children
Essentials of Genetics and Early Neurodevelopment
Neurodevelopmental Evidence and Schizophrenia
Abnormalities of Children Vulnerable to Schizophrenia
Summary and Conclusions
8: Flights of Theory
Root Problems for Theories of Schizophrenia
Schizotaxia, Schizotypy and Schizophrenia
Neurodevelopmental Diathesis-Stress Theories
Summary and Synthesis
9: The End of the Beginning
The Neuroscience Sweepstakes
The Promissory Note
Multiple Disease States
The Anomaly at the Frontier of Mind and Brain
Conclusion
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