Anticancer agents : frontiers in cancer chemotherapy
著者
書誌事項
Anticancer agents : frontiers in cancer chemotherapy
(ACS symposium series, 796)
American Chemical Society, c2001
大学図書館所蔵 全8件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
Describes cutting edge approaches in the development of anticancer agents for chemotherapy. These new and interdisciplinary approaches are aimed at the development of tumor specific anticancer agents while increasing the potency against drug-resistant tumors. The volume includes an overview of new paradigms for cancer drug discovery and development by NCI, new generation cytotoxic agents, mechanism based enzyme inhibitors as anticancer agents, anti-angiogenesis
agents, antitumor vaccins, and tumor activated prodrugs using immunoconjugates of monoclonal antibodies with cytotoxic agents.
目次
- Preface
- 1. Cancer Drug Discovery and Development: New Paradigms for a New Millennium
- 2. Evolutionary Biosynthesis of Anticancer Drugs
- 3. Some Recent Developments in the Synthesis and SAR of Novel Taxanes
- 4. New Generation Taxoids and Hybrids of Microtube-Stabilizing Anticancer Agents
- 5. Discodermolide and Taxol: A Synergistic Drug Combination in Human Carcinoma Cell Lines
- 6. Highly Efficient Semisynthesis of Biologically Active Epothilone Derivatives
- 7. Synthetic and Semisynthetic Analogs of Epothilones: Chemistry and Biological Activity
- 8. Synthesis and Biological Activity of Epothilones
- 9. Epothelones and Sarcodictyins: From Combinatorial to Designed Analogs
- 10. Synthesis and Structure-Activity Relationship Studies of Cryptophycins: A Novel Class of Potent Antimitotic Tumor Depsipeptides
- 11. Farnesyltransferase Inhibitors as Potential Anticancer Agents
- 12. Farnesyltransferase Inhibitors: From Squalene Synthase Inhibitors to the Clinical Agent BMS-214662
- 13. Inhibiting Farnesyl Protein Transferase with Sch-66336: Potentially a Selective Non-Cytotoxic herapy for Human Cancer
- 14. Pyrrolo[2,3-d]pyrimidine and Pyrazolo[3,4-d]pyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase
- 15. STI571: A New Treatment Modality for CML
- 16. The Discovery and Development of Second-Generation Matrix Metalloproteinase Inhibitors for the Treatment of Cancer
- 17. Prospects for Anti-Angiogenic Therapies Based upon VEGF Inhibition
- 18. Carbohydrate-Based Tumor Antigens as Anti-Tumor Vaccine Agents
- 19. Drugs to Enhance the Therapeutic Potency of Anti-Cancer Antibodies
- Author Index
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