Anticancer agents : frontiers in cancer chemotherapy
Author(s)
Bibliographic Information
Anticancer agents : frontiers in cancer chemotherapy
(ACS symposium series, 796)
American Chemical Society, c2001
Available at 8 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
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  United States of America
Note
Includes bibliographical references and indexes
Description and Table of Contents
Description
Describes cutting edge approaches in the development of anticancer agents for chemotherapy. These new and interdisciplinary approaches are aimed at the development of tumor specific anticancer agents while increasing the potency against drug-resistant tumors. The volume includes an overview of new paradigms for cancer drug discovery and development by NCI, new generation cytotoxic agents, mechanism based enzyme inhibitors as anticancer agents, anti-angiogenesis
agents, antitumor vaccins, and tumor activated prodrugs using immunoconjugates of monoclonal antibodies with cytotoxic agents.
Table of Contents
- Preface
- 1. Cancer Drug Discovery and Development: New Paradigms for a New Millennium
- 2. Evolutionary Biosynthesis of Anticancer Drugs
- 3. Some Recent Developments in the Synthesis and SAR of Novel Taxanes
- 4. New Generation Taxoids and Hybrids of Microtube-Stabilizing Anticancer Agents
- 5. Discodermolide and Taxol: A Synergistic Drug Combination in Human Carcinoma Cell Lines
- 6. Highly Efficient Semisynthesis of Biologically Active Epothilone Derivatives
- 7. Synthetic and Semisynthetic Analogs of Epothilones: Chemistry and Biological Activity
- 8. Synthesis and Biological Activity of Epothilones
- 9. Epothelones and Sarcodictyins: From Combinatorial to Designed Analogs
- 10. Synthesis and Structure-Activity Relationship Studies of Cryptophycins: A Novel Class of Potent Antimitotic Tumor Depsipeptides
- 11. Farnesyltransferase Inhibitors as Potential Anticancer Agents
- 12. Farnesyltransferase Inhibitors: From Squalene Synthase Inhibitors to the Clinical Agent BMS-214662
- 13. Inhibiting Farnesyl Protein Transferase with Sch-66336: Potentially a Selective Non-Cytotoxic herapy for Human Cancer
- 14. Pyrrolo[2,3-d]pyrimidine and Pyrazolo[3,4-d]pyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase
- 15. STI571: A New Treatment Modality for CML
- 16. The Discovery and Development of Second-Generation Matrix Metalloproteinase Inhibitors for the Treatment of Cancer
- 17. Prospects for Anti-Angiogenic Therapies Based upon VEGF Inhibition
- 18. Carbohydrate-Based Tumor Antigens as Anti-Tumor Vaccine Agents
- 19. Drugs to Enhance the Therapeutic Potency of Anti-Cancer Antibodies
- Author Index
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