Applied statistics in the pharmaceutical industry : with case studies using S-Plus
著者
書誌事項
Applied statistics in the pharmaceutical industry : with case studies using S-Plus
Springer, c2001
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Providing a general guide to statistical methods used in the pharmaceutical industry, and illustrating how to use S-PLUS to implement these methods, the book explains why S-PLUS is a useful software package and discusses the results and implications of each particular application. It is targeted at graduates in biostatistics, statisticians involved in the industry as research scientists, regulators, academics, and/or consultants who want to know more about how to use S-PLUS and learn about other sub-fields within the industry, as well as statisticians in other fields who want to know more about statistical applications in the pharmaceutical industry.
目次
Statistics and the Drug Development Process, Bruce Rodda and Steven P. Millard * One-Factor Comparative Studies, Bill Pikounis * Analysis of Animal Carcinogenicity Data, Hongshik Ahn and Ralph L. Kodell * Analysis of Toxicokinetic and Pharmacokinetic Data from Animal Studies, Wherly P. Hoffman, Michael A. Heathman, James Z. Chou, and Darrel L. Allen * Analysis of Pharmacokinetic Data, Ha Nguyen and Dhammika Amaratunga * Graphical Presentation of Single Patient Results, Jurgen Bock * Graphical Insight and Data Analysis for the 2, 2, 2, Crossover Design, Bill Pikounis, Tom Bradstreet, and Steven P. Millard * Design and Analysis of Phase I Trials in Clinical Oncology, Axel Benner, Lutz Elder, and Gernot Hartung * Patient Compliance and its Impact on Steady State Pharmacokinetics, Wenping Wang * Analysis of Analgesic Trials, Ene I. Ette, Peter Lockwood, Raymond Miller, and Jaap Mandema * Power and Sample Size Calculations, Jurgen Bock * Comparing Two Treatments in a Large Phase III Clinical Trial, Michaela Jahn * Analysis of Variance: A Comparison Between SAS and S-PLUS, Melvin Olson * Permutation Tests for Phase III Clinical Trials, Vance Berger and Anastasia Ivanova * Sample Size Reestimation, Wenping Wong and Andreas Krause * Meta-Analysis of Clinical Trials, Keith O'Rourke, Beverley Shea, and George A. Wells * Analysis of Health Economic Data, John R. Cook, George W. Carides, and Erik J. Dasbach * Evaluation of the Decimal Reduction Time of a Sterilization Process in Parmaceutical Production, Jeffrey Eisele, Mauro Gasparini, and Amy Racine * Acceptance Sampling Plans by Attributes, Harry Yang and David Carlin
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