Applied electrospray mass spectrometry
著者
書誌事項
Applied electrospray mass spectrometry
(Practical spectroscopy, v. 32)
Marcel Dekker, c2002
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Discussing strategies to determine the structure and machanisms of numerous compound classics, this book covers new chemical and elctrophoretic techniques for rapid sample preconcentration and separation. It summarizes breakthroughs in the theory and instrumentation of electrospray mass spectrometry in pharmaceutical and biomedical applications, provides practical examples for the characterization of peptides, proteins, and glycoproteins, includes applications in proteomics, combinatorial chemistry, and drug characterization. Topics include chemical and electrophoretic techniques for rapid sample preconcentration and separation, screening processes for proteins from libraries of compounds, protein folding and dynamics, and more.
目次
- Historical review/principles/instrumentation
- nano-spray ESI development - LC/MS, CE/MS application
- antibiotics/pharmaceuticals
- pharmacokinetics/drug metabolism
- proteins/peptides
- glyco-proteins
- proteomics/bioinformatics
- noncovalent complexes
- H/D exchange in solution
- clinical biomedical application - micro-flow ESI.
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