Telomeres
Author(s)
Bibliographic Information
Telomeres
（Cold Spring Harbor monograph series, 29）
UMI Proquest company, 2002
Reproduction
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Note
Reprint. Originally published: New York : Cold Spring Harbor Laboratory Press , 1995
Includes bibliographical references and index
Printed by xerographic process on acid-free paper
Description and Table of Contents
Description
Research on telomeres has recently surged forward. Telomeres have been found to shorten in neoplastic and aging cells, and their analysis has been stimulated by the molecular cloning of key components in telomere metabolism. This book offers a comprehensive account of telomere structure and function in a variety of organisms, including yeast, Drosophila, ciliates, plants and mammals. Starting with a historical overview, it covers telomere structure, dynamics, localization, transcriptional silencing, as well as the significance of length regulation and the roles of telomeres. Written and edited by members of leading laboratories, the book should be of use to investigators of cancer and aging, as well as those with interests in replication, ribonuclear particles, chromosome dynamics and polymerases.
Table of Contents
- Beginning of the end - origins of the telomere concept, J.G. Gall
- telomere DNA structure, E. Henderson
- telomerase biochemistry and regulation, C.W. Greider
- telomere proteins, G. Fang, T.R. Cech
- saccharomyces telomeres - function, structure and replication, V.A. Zakian
- telomere position effects and transcriptional silencing in the yeast saccharomyces cerevisiae, D. Shore
- developmentally programmed healing of chromosomes, E.H. Blackburn
- non-programmed and engineered chromosome breakage, H. Cooke
- telomeres and ageing, C.B. Harley
- telomere dynamics and genome instability in human cancer, T. de Lange
- cytology of telomeres, A.F. Dernburg, et al
- Drosophila telomeres - another way to end it all, M.L. Pardue
- plant telomeres, E.J. Richards.
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