Mitochondria in pathogenesis
著者
書誌事項
Mitochondria in pathogenesis
Kluwer Academic/Plenum Publishers, c2001
大学図書館所蔵 全6件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Mitochondria are organelles in each cell outside the nucleus and are the energy source of all cells. As such, they are crucial to the healthy functioning of cells. Recent research has shown that mitochondrial dysfunction underlies a broad spectrum of disease, from maternally inherited genetic disorders to metabolism defects, aging, stroke, and neurodegenerative diseases such as Parkinson's, Alzheimer's, and Lou Gehrig's disease. This book brings together top researchers whose work in examining the pathophysiologic processes will lead to new strategies for prevention and treatment.
目次
Evaluation of Mitochondrial Function in Intact Cells.- Flow Cytometric Analysis of Mitochondrial Function.- Confocal Microscopy of Mitochondrial Function in Living Cells.- Mitochondrial Disease and Aging.- Primary Disorders of Mitochondrial DNA and the Pathophysiology of mtDNA-Related Disorders.- Transmission and Segregation of Mammalian Mitochondrial DNA.- Cardiac Reperfusion Injury: Aging, Lipid Peroxidation, and Mitochondrial Function.- Mitochondrial Ion Homeostasis and Necrotic Cell Death.- Ca2+-Induced Transition in Mitochondria: A Cellular Catastrophe?.- Physiology of the Permeability Transition Pore.- Control of Mitochondrial Metabolism by Calcium-Dependent Hormones.- The Permeability Transition Pore in Myocardial Ischemia and Reperfusion.- Mitochondrial Calcium Dysregulation during Hypoxic Injury to Cardiac Myocytes.- Mitochondrial Implication in Cell Death.- Role of Mitochondria in Apoptosis Induced by Tumor Necrosis Factor-?.- The ATP Switch in Apoptosis.- Mitochondria, Free Radicals, and Disease.- Reactive Oxygen Generation by Mitochondria.- Role of the Permeability Transition in Glutamate-Mediated Neuronal Injury.- Mitochondrial Dysfunction in the Pathogenesis of Acute Neural Cell Death.- Varied Responses of Central Nervous System Mitochondria to Calcium.- Mitochondrial Dysfunction in Oxidative Stress, Excitotoxicity, and Apoptosis.- Mitochondria in Alcoholic Liver Disease.- Mitochondrial Changes after Acute Alcohol Ingestion.- Mitochondrial Dysfunction in Chronic Fatigue Syndrome.- Chemical Toxicity.- Bile Acid Toxicity.- Reye’s Syndrome and Related Chemical Toxicity.- Purinergic Receptor-Mediated Cytotoxicity.- Doxorubicin-Induced Mitochondrial Cardiomyopathy.- Drug-Induced Microvesicular Steatosis and Steatohepatitis.
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