Chronic lymphoid leukemias

書誌事項

Chronic lymphoid leukemias

edited by Bruce D. Cheson

(Basic and clinical oncology, 26)

Marcel Dekker, c2001

2nd ed., rev. and expanded

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注記

Includes bibliographical references and index

Rev. ed. of: Chronic lymphocytic leukemia c1993.

内容説明・目次

内容説明

Written by over 50 internationally distinguished experts, 30 more than the first edition, and contains nine new chapters! Continuing in the esteemed tradition and heralded success of the first edition, Chronic Lymphoid Leukemias, Second Edition offers a full overview of chronic lymphocytic leukemia (CLL) from multiple perspectives-covering all major developments since the previous edition was published eight years ago. Chronicling the complete history and variations of CLL-type leukemia, the Second Edition reviews the origin, nature, and molecular differences between B-CLL and T-CLL/PLL leukemias analyzes core constituents of apoptosis and causes for dysregulation of programmed cell death (PCD) in B-CLL examines recent research on the role cytokines and regulatory molecules may play in cross-cell communication profiles commonly used vectors for somatic gene therapy, as well as the latest advances in genetic engineering and vector design and production utilizes up-to-the-minute techniques such as fluorescence in-situ hybridization (FISH) and comparative genomic hybridization (CGH) to detect genetic abnormalities and aberrations explores current measures of supportive care with splenectomy, cytokine proteins, and intravenous immunoglobulin applications identifies how to manage infectious and psychiatric complications in patients with CLL and much more! Provides contemporary results on the efficacy of nucleoside analog combinations such as ara-C with fludarabine and cladribine and on the emerging nucleosides nelarabine and clofarabine! Copiously supplemented with over 2500 literature references-1000 more than the first edition-Chronic Lymphoid Leukemias, Second Edition fulfills the reference needs of oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists, molecular biologists, and medical school students in these disciplines.

目次

History of Chronic Lymphocytic Leukemia Kanti R. Rai and Tarun Wasil Molecular Biology of Chronic Lymphocytic Leukemia Florencia Bullrich and Carlo M. Croce Chronic Lymphocytic Leukemia: Epidemiological, Familial, and Genetic Aspects Maria T. Sgambati, Martha S. Linet, and Susan S. Devesa The Origin and Nature of the Chronic Lymphocytic Leukemia Lymphocyte Paolo Ghia and Federico Caligaris-Cappio Immunoglobulin Variable Region Gene Characteristics and Surface Membrane Phenotype Define B-CLL Subgroups with Distinct Clinical Courses Nicholas Chiorazzi and Manlio Ferrarini Apoptosis Dysregulation in Chronic Lymphocytic Leukemia John C. Reed and Shinichi Kitada Cytokines and Regulatory Molecules in the Pathogenesis and Clinical Course of B-Cell Chronic Lymphocytic Leukemia Enrica Orsini and Robin Foa Randomized Trials: What Do They Teach us About Chronic Lymphocytic Leukemia Treatment? G. Dighiero Genetic Approaches to the Therapy of Chronic Lymphocytic Leukemia Thomas J. Kipps Combination Strategies for Purine Nucleoside Analogs Varsha Gandhi and William Plunkett Differential Diagnosis of the Chronic B-Cell Lymphoid Leukemias Randy D. Gascoyne Prognostic Factors in Chronic Lymphocytic Leukemia Stefano Molica Initial Approach to the Patient with Chronic Lymphocytic Leukemia Bruce D. Cheson Management of the Patient with Relapsed or Refractory Chronic Lymphocytic Leukemia Deborah A. Thomas, Susan M. O'Brien, and Michael J. Keating The Use of Therapeutic Monoclonal Antibodies in Chronic Lymphocytic Leukemia Martin J. S. Dyer and Anders OEsterborg Genomic Aberrations in B-Cell Chronic Lymphocytic Leukemia Stephan Stilgenbauer, Peter Lichter, and Hartmut Doehner Developing Risk-Adapted Treatment Strategies for Chronic Lymphocytic Leukemia Emilio Montserrat High-Dose Therapy and Stem Cell Support in Chronic Lymphocytic Leukemia Angela M. Krackhardt and John G. Gribben Finding New Therapies for Patients with Chronic Lymphocytic Leukemia John C. Byrd and Michael R. Grever Autoimmune Disease and Its Management in Chronic Lymphocytic Leukemia Terry Hamblin Richter's Syndrome John Seymour and Janine Campbell Supportive Care in Chronic Lymphocytic Leukemia Farhad Ravandi, Michael J. Keating, and Susan M. O'Brien Infections in Patients with Chronic Lymphocytic Leukemia: Pathogenesis, Spectrum, and Therapeutic Approaches Vicki A. Morrison Prolymphocytic Leukemia of B- and T-Cell Types: Biology and Therapy Estella Matutes, Vasantha Brito-Babapulle, Claire Dearden, M. R. Yullie, and Daniel Catovsky Chronic T-Cell and NK-Cell Leukemias Edgar G. Miranda and Thomas P. Loughran, Jr. Current Concepts in the Management of Hairy Cell Leukemia Martin S. Tallman, Mark A. Hoffman, and LoAnn C. Peterson Psychological Aspects of Chronic Lymphoid Leukemia Jahandar Saifollahi, Marjaneh Rouhani, Andrew J. Roth, and Jimmie C. Holland

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