Promises and limits of reductionism in the biomedical sciences

Bibliographic Information

Promises and limits of reductionism in the biomedical sciences

edited by Marc H.V. Van Regenmortel, David L. Hull

John Wiley & Sons, c2002

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"... presentations made ... at the Philippe Laudat Conference on 'Promises and Limits of Reductionism in the Biomedical Sciences', held at the Abbey of Royaumont, north of Paris, on 22-24 May 2000"--Pref

Includes bibliographical references (p. 365-367) and index

Description and Table of Contents

Description

Reductionism as a scientific methodology has been extraordinarily successful in biology. However, recent developments in molecular biology have shown that reductionism is seriously inadequate in dealing with the mind-boggling complexity of integrated biological systems. This title presents an appropriate balance between science and philosophy and covers traditional philosophical treatments of reductionism as well as the benefits and shortcomings of reductionism in particular areas of science. Discussing the issue of reductionism in the practice of medicine it takes into account the holistic and integrative aspects that require the context of the patient in his biological and psychological entirety. The emerging picture is that what first seems like hopeless disagreements turn out to be differences in emphasis. Although genes play an important role in biology, the focus on genetics and genomics has often been misleading. The consensus view leads to pluralism: both reductionst methods and a more integrative approach to biological complexity are required, depending on the questions that are asked. * An even balance of contributions from scientists and philosophers of science - representing a unique interchange between both communities interested in reductionism

Table of Contents

Preface Contributors About the Editors Introduction (D.L. Hull and M.H.V. Van Regenmortel) Emergent Properties of Biological Molecules and Cells (R. P. J. Williams) From Nineteenth Century Ideas on Reduction in Physiology to Non-reductive Explanations in Twentieth Century Biochemistry (C. Debru) Pitfalls of Reductionism in Immunology (M. H. V. Van Regenmortel) Reductionism in Medicine: Social Aspects of Health (E.A. Lloyd) 'Who's Afraid of Reductionism?' 'I am!' (S. Shostak) Round Table Discussion 1 (Chair: A. Rosenberg) Reductionism in a Historical Science (A. Rosenberg) Varieties of Reductionism: Derivation and Gene Selection (D. L. Hull) The Gene: Between Holism and Reductionism (M. Morange) Genes versus Molecules: How to, and How Not To, Be a Reductionist (S. Sarak) Limits on Reproduction: A Reductionist Research Strategy in Evolutionary Biology (J. Griesemer) Evolutionary Psychology: A Case Study in the Poverty of Genetic Determinism (J. Dupre) Round Table Discussion 2 (Chair: M.H.V. Van Regenmortel) The Ethical Imperative of Holism in Medicine (A. Tauber) Levels of Explanation in Human Behaviour: the Poverty of Evolutionary Psychology (S. P. R. Rose) Reductionism and Social Policy (D. Nelkin) Reductionism, Complexity and Molecular Medicine: Genetic Chips and the 'Globalization' of the Genome (K. Schaffner) Round Table Discussion 3 (Chair: K.F. Schaffner) Bibliography Index

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