Karch's pathology of drug abuse
著者
書誌事項
Karch's pathology of drug abuse
CRC Press, c2002
3rd ed
- タイトル別名
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Pathology of drug abuse
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注記
Previous ed. published as: Pathology of drug abuse. 1996
LCCN:2001036559
内容説明・目次
内容説明
AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST
The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. It covers in detail the clinical consequences of drug usage and provides the latest information on clinical aspects of drug abuse. This well-written, extensively referenced resource supplies a mixture of clinical information and pathology findings.
SEE WHAT'S NEW IN THE THIRD EDITION:
New information on methamphetamine abuse
New chapter on GHB, ketamine, and select herbal hallucinogens
New micrographs showing pathology of drug related deaths
Over 1000 new references
The mechanism of sudden death in cocaine users and overdose in heroin abusers
Toxicology and pathology of ephedrine
Neurochemistry of excited delirium
Psychotic behavior in stimulant abusers
About the author: Steven B. Karch has appeared as an expert witness in international cases, including advice to counsel in the Harold Shipman murder trial. He is an assistant medical examiner in San Francisco, where he consults on cases of drug-related deaths. He received his bachelors degree from Brown University, did graduate work in cell biology and biophysics at Stanford, and received his M.D. from Tulane University Medical School.
目次
COCAINE
Incidence
Epidemiology
History
Cultivation and Manufacture
Drug Constants
Routes of Ingestion
Metabolism of Cocaine and Its Metabolites
Problems of Test Interpretation
Cocaine Tissue Disposition
Cocaine's Effects on Catecholamine and the Heart
External Markers of Cocaine Abuse
Toxicity by Organ System
When is Cocaine the Cause of Death?
OTHER NATURALLY OCCURRING STIMULANTS
Absinthe
Caffeine
Ephedrine
Khat
SYNTHETIC STIMULANTS
Amphetamine and Methamphetamine
Methylphenidate (Ritalin (TM))
Phenylpropanolamine
Fenfluramine
HALLUCINOGENS
Phenylethylamine Derivatives
Substituted Amphetamines (Phenylisopropylamines)
Phenylalkylamines
NARCOTICS
Incidence
Epidemiology
Classification of Narcotic Agents
History of Opiate Abuse
Cultivation and Manufacture
Opiate Classification
Interpretation of Blood and Tissue Concentrations
Medical Consequences of Opiate Abuse
Pulmonary Disorders
DISASSOCIATIVE ANESTHETICS
Phencyclidine
Ketamine
Gamma-hydroxybutyrate (GHB)
ANABOLIC STEROIDS
Incidence
Epidemiology
History
Steroid Abuse
Pharmacology
Steroid-related Disorders
Detecting Steroid Abuse
SOLVENTS
Incidence
Epidemiology
General considerations
Absorption and tissue disposition
Clinical syndromes
Appendix 1: Conversion Formulas
Appendix 2: Blood Alcohol Concentrations
Appendix 3: Volume of Distribution Calculations
Appendix 4: Normal Heart Weights
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