Atherosclerosis : gene expression, cell interactions, and oxidation
著者
書誌事項
Atherosclerosis : gene expression, cell interactions, and oxidation
Oxford University Press, c2000
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book provides a critical review of the oxidative theory of atherosclerosis as well as highlighting new trends in research from basic to clinical, academic to commercial. The contributions of diabetes, vascular dysfunction, blood coagulation, plaque rupture, oxidative stress, lymphocytes, macrophages, growth factors, cytokines, and oxysterols to atherogenesis are all discussed, as are the roles of smooth muscle and endothelial cells. As well as a summary of the
current methods of diagnosis and the future prospect of using biochemical markers from plasma is also discussed. There is a critical look at gene therapy and other future therapeutic strategies based on the molecular and cellular causes of atherosclerosis. Each chapter is written by two or more
authors from different laboratories to ensure a balanced approach. It will be invaluable to all biomedical researchers with a specialist or passing interest in atherosclerosis research.
目次
- THE MORPHOLOGY AND NATURAL HISTORY OF ATHEROSCLEROSIS
- DIABETES AND ATHEROSCLEROSIS
- ANTIOXIDANT INTERVENTION STUDIES IN SMALL ANIMALS
- ANTIOXIDANT INTERVENTION STUDIES IN HUMANS
- VASCULAR DYSFUNCTION AND ITS CONTRIBUTION TO ATHEROSCLEROSIS
- GENE THERAPY FOR VASCULAR DISEASES: CLOSER TO DELIVERING THE GOODS
- THE ENDOTHELIAL CELL IN ATHEROSCLEROSIS
- OXIDATIVE STRESS AND PLATELET FORMATION IN ATHEROSCLEROSIS
- MACROPHAGE LIPID METABOLISM AND ATHEROSCLEROSIS
- SMOOTH MUSCLE CELLS AND THE CONNECTIVE TISSUE MATRIX OF THE INITIMA
- LYMPHOCYTES IN ATHEROGENESIS
- GROWTH FACTORS AND CYTOKINES IN ATHEROGENESIS
- LIPOPROTEIN INFLUX AND EFFLUX IN THE ATHEROSCLEROTIC INTIMA
- INHIBITION OF THE CYTOKINE-INDUCED EXPRESSION OF ENDOTHELIAL CELL ADHESION MOLECULES BY HIGH DENSITY LIPOPROTEINS
- PROTEIN OXIDATION IN ATHEROGENESIS
- ANTI-OXIDANTS AND CO-ANTIOXIDATION IN LIPOPROTEINS AND THE INTIMA
- OXYSTEROLS IN ATHEROGENESIS
- INTRACELLULAR EFFECTS OF CELL SURFACE-LOCALIZED INITIATION OF BLOOD COAGULATION
- PLAQUE RUPTURE AND ITS CONSEQUENCES
- DIAGNOSIS AND THERA
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