Microarrays for an integrative genomics

著者

    • Kohane, Isaac S.
    • Kho, Alvin T.
    • Butte, Atul J.

書誌事項

Microarrays for an integrative genomics

Isaac S. Kohane, Alvin T. Kho, and Atul J. Butte

(Computational molecular biology)

MIT Press, c2003

大学図書館所蔵 件 / 20

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.

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