Mitochondrial function and dysfunction
著者
書誌事項
Mitochondrial function and dysfunction
（International review of neurobiology, v. 53）
Academic Press, c2002
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Mitochondria are critical to the survival of cells, therefore, it is not surprising that abnormalities in mitochondrial function may lead to human disease. This book concentrates on the biology and pathology of mitochondria, covering some ot the important basic science features of the biology of mitochondria. It then moves on to discuss the breadth of human diseases related to mitochondrial dysfunction, including Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Alzheimer's disease.
目次
- Mitochondrial Structure and Function: Mitochondrial DNA structure and function. Oxidative phosphorylation
- structure, function and intermediary metabolism. Import of mitochondrial proteins. Primary Respiratory Chain Disorders: Mitochondrial Disorders of the Nervous System: Clinical, biochemical and molecular genetic features. Secondary Respiratory Chain: Disorders Friedriech's ataxia. Wilson's disease. Hereditary spastic paraplegia. Cytochrome c oxidase deficiency. Toxin Induced Mitochondrial Dysfunction: Toxin Induced Mitochondrial Dysfunction. Neurodegenerative Disorders: Parkinson's disease. Huntington's Disease: The Mystery Unfolds? Alzheimer's disease. Mitochondria and Amylotrophic Lateral Sclerosis. Models of Mitochondrial Disease: Models of Mitochondrial Disease. Apoptosis: Contributions of Mitochondrial Alterations, Resulting from Bad Genes and a Hostile Environment, to the Pathogenesis of Alzheimer's Disease. Defects of ss-Oxidation Including Carnitine Deficiency: Defects of ss-Oxidation Including Carnitine Deficiency. Mitochondrial Involvement in Aging: The Mitochondrial Theory of Aging: Involvement of mtDNA Damage and Repair.
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