Endocrine control of skeletal maturation : annotation to bone age readings

書誌事項

Endocrine control of skeletal maturation : annotation to bone age readings

Ze'ev Hochberg

Karger, c2002

大学図書館所蔵 件 / 3

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

As a common concept 'bone age' is felt to be an expression of the biological maturity of a child. Inferring from bone maturity, the clinician can contemplate diagnostic considerations and evaluate height prediction. A radiogram of the hand and wrist may provide additional information that is not being evaluated by reading of a 'bone age'. Although it reveals only calcified elements it provides a glimpse into a whole variety of processes in bone and cartilage growth, differentiation and calcification which, in turn, are regulated by control mechanisms. Thyroid hormones, sex steroids, calcium regulating hormones are but a few of these control mechanisms, and their effect may become evident when radiograms are carefully examined. This book illustrates how to interpret the biological mechanisms of growth from hand and wrist x-rays reviewing at the same time the anatomical and histological maturation of long bones and cuboid bones. It summarizes the endocrine regulation of these maturational processes and attempts to uncover endocrine functions and malfunctions as they unfold in the radiogram. The presently used methods of skeletal maturity assessment are outlined and reiterated, while some doubts about the entire paradigm and its uncertainties are to be raised and considered. This book is an indispensable aid enabling endocrinologists, radiologists and pediatricians to understand skeletal maturity in a more meaningful way.

目次

  • Bone Maturation and Growth: Primary and Secondary Ossification Centres
  • Longitudinal Growth at the Growth Plate
  • Chondroplasia W Osteogenesis
  • Fusion of Primary and Secondary Ossification Centres
  • Direction of Growth
  • Marginal Regions of the Growth Plate
  • Cuboid Bones (Carpals and Vertebrae)
  • Implications for Skeletal Maturity Readings. Radiographic Perception: Demarcation Line
  • Chondroplasia and Osteogenesis
  • Growth Arrest Lines
  • Normal Variations
  • Maturational Sequence
  • Other Imaging Tools. Endocrine Regulation of Bone Maturation: Growth Hormone - IGF-1 Axis
  • Physiological Considerations W Implications for Skeletal Maturity Readings
  • Thyroid Hormones
  • Physiological Considerations W Implications for Skeletal Maturity Readings. Sex Steroids (Gonadal and Adrenal): Physiological Considerations W Delayed and Precocious Puberty W Turner Syndrome W Multiple Hormone Deficiency W
  • Implications for Skeletal Maturity Readings
  • Calcium-Regulating Hormones
  • Physiological Considerations W Implications for Skeletal Maturity Readings
  • Glucocorticoids
  • Physiological Considerations W Implications for Skeletal Maturity Readings
  • Other Diseases of Bone Growth and Maturation
  • Obesity
  • Scurvy
  • Marfan Syndrome
  • Renal Failure. Assessment of Skeletal Maturity - Critical Comments: Greulich and Pyle Atlas Method
  • TW2 Individual Bones Method
  • Adult Height Prediction
  • Skeletal Maturity as an Argument in Functions
  • Practical Guidelines
  • Osteoporosis.

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