Retroviral immunology : immune response and restoration
Author(s)
Bibliographic Information
Retroviral immunology : immune response and restoration
(Infectious disease)
Humana Press, c2001
Available at 7 libraries
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Although there have been many books on HIV and AIDS, surprisingly little has been published that focuses on the immunology of retroviral infections in general, and HIV in particular. Retroviral Immunology: Immune Response and Restoration is the first book of its kind to address the most important aspects of the immunology of retroviruses, including not only the virus-specific immune responses, but also genetic and virologic factors modulating these responses. The book also deals directly with the emerging concept of immune restora tion in retroviral infections, a particularly important subject to the thousands of clinicians who deal with this problem on a daily basis. With the advent of highly effective antiviral drug regimens to slow down the replication of HIV and the progression of AIDS, new challenges and opportunities are arising. Restoration of general immune function has brought with it not only complica tions of immune restoration-mediated disease, but also the realistic hope for meaningful restoration of the ability to control HIV replication with the immune system. Leading scientists in the field have summarized the most current informa tion regarding experimental and clinical aspects of retroviral infections. Retroviral Immunology: Immune Response and Restoration should prove an impor tant point of reference for basic scientists and clinicians in this area of research. We are indebted to all of our authors for their excellent contributions.
Table of Contents
Epidemiological and Immunological Implications of the Global Variability of HIV-1
Bette T. Korber, Brian Foley, Brian Gaschen, and Carla Kuiken
Role of Chemokines and Their Receptors in the Pathogenesis of HIV Infection
Frederick S. Lee, Gabriele Kuschert, Otto O. Yang, and Andrew D. Luster
Cytokines and Chemokines in HIV Infection
Guido Poli
Development and Reconstitution of T-Lymphoid Immunity
Krishna V. Komanduri and Joseph M. McCune
HIV Gene Products as Manipulators of the Immune System
Aram Mangasarian and Didier Trono
Immune Response to Murine and Feline Retroviruses
Daniela Finke and Hans Acha-Orbea
Immune Response to HTLV-I and HTLV-II
Samantha S. Soldan and Steven Jacobson
HIV-Specific Neutralizing Antibodies
David C. Montefiori
Cytotoxic T-Cell Responses in Acute and Chronic HIV-1 Infection
Hugo Soudeyns and Giuseppe Pantaleo
Characterization of the HIV-1-Specific T-Helper Cell Response
Bruce D. Walker
Immune Responses to Nonhuman Primate Lentiviruses
Amitinder Kaur, Marie-Claire Gauduin, and R. Paul Johnson
Intrahost Selective Pressure and HIV-1 Heterogeneity During Progression to AIDS
Vladimir V. Lukashov and Jaap Goudsmit
Polymorphism in HLA and Other Elements of the Class I and II Response Pathways
Richard A. Kaslow and R. Pat Bucy
Immunologic Approaches to the Therapy of Patients with HIV Infection
H. Clifford Lane and Scott Seeley
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