Retroviral immunology : immune response and restoration

Bibliographic Information

Retroviral immunology : immune response and restoration

edited by Giuseppe Pantaleo and Bruce D. Walker

(Infectious disease)

Humana Press, c2001

Available at  / 7 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Although there have been many books on HIV and AIDS, surprisingly little has been published that focuses on the immunology of retroviral infections in general, and HIV in particular. Retroviral Immunology: Immune Response and Restoration is the first book of its kind to address the most important aspects of the immunology of retroviruses, including not only the virus-specific immune responses, but also genetic and virologic factors modulating these responses. The book also deals directly with the emerging concept of immune restora tion in retroviral infections, a particularly important subject to the thousands of clinicians who deal with this problem on a daily basis. With the advent of highly effective antiviral drug regimens to slow down the replication of HIV and the progression of AIDS, new challenges and opportunities are arising. Restoration of general immune function has brought with it not only complica tions of immune restoration-mediated disease, but also the realistic hope for meaningful restoration of the ability to control HIV replication with the immune system. Leading scientists in the field have summarized the most current informa tion regarding experimental and clinical aspects of retroviral infections. Retroviral Immunology: Immune Response and Restoration should prove an impor tant point of reference for basic scientists and clinicians in this area of research. We are indebted to all of our authors for their excellent contributions.

Table of Contents

Epidemiological and Immunological Implications of the Global Variability of HIV-1 Bette T. Korber, Brian Foley, Brian Gaschen, and Carla Kuiken Role of Chemokines and Their Receptors in the Pathogenesis of HIV Infection Frederick S. Lee, Gabriele Kuschert, Otto O. Yang, and Andrew D. Luster Cytokines and Chemokines in HIV Infection Guido Poli Development and Reconstitution of T-Lymphoid Immunity Krishna V. Komanduri and Joseph M. McCune HIV Gene Products as Manipulators of the Immune System Aram Mangasarian and Didier Trono Immune Response to Murine and Feline Retroviruses Daniela Finke and Hans Acha-Orbea Immune Response to HTLV-I and HTLV-II Samantha S. Soldan and Steven Jacobson HIV-Specific Neutralizing Antibodies David C. Montefiori Cytotoxic T-Cell Responses in Acute and Chronic HIV-1 Infection Hugo Soudeyns and Giuseppe Pantaleo Characterization of the HIV-1-Specific T-Helper Cell Response Bruce D. Walker Immune Responses to Nonhuman Primate Lentiviruses Amitinder Kaur, Marie-Claire Gauduin, and R. Paul Johnson Intrahost Selective Pressure and HIV-1 Heterogeneity During Progression to AIDS Vladimir V. Lukashov and Jaap Goudsmit Polymorphism in HLA and Other Elements of the Class I and II Response Pathways Richard A. Kaslow and R. Pat Bucy Immunologic Approaches to the Therapy of Patients with HIV Infection H. Clifford Lane and Scott Seeley

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