Brain imaging using PET
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書誌事項
Brain imaging using PET
Academic Press, c2002
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注記
"An imprint of Elsevier Science"
Includes bibliographical references and index
内容説明・目次
内容説明
Discussing not only PET technique and instrumentation, but new developments in a broad range of fields such as kinetics, enzyme/neurotransmitter transport, language acquisition, and neuropathology, Brain Imaging Using PET will appeal to both PET experts and non-PET users in many branches of neuroscience. The authors offer an invaluable analysis of brain imaging and techniques, providing everything from the foundations to the practical applications of the modern techniques used in PET.
目次
Contributors
Preface
Acknowledgments
Part I Instrumentation
1. Correction of Head Movement Using an Optical Motion Tracking System during PET Study with Rhesus Monkey
I. Introduction
II. Materials and Methods
III Results and Discussion
2. The Effect of Activity from Outside the Field of View on Accurate Quantification of 3D PET Images
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
3. Delay and Dispersion Correction for a New Coincidential Radioactivity Detector, Pico-Count, in Quantitative PET Studies
I. Introduction
II. Materials and Methods
III. Results and Discussion
Part II Kinetic Analysis
4. Neuroreceptor Imaging: Considerations for Design, Data Analysis, and Interpretation
I. Introduction
II. Radioligand
III. Is Quantification Needed?
IV. Image Fusion
V. Experimental Design
VI. Clinical Use of Neuroreceptor Imaging
5. Quantification of -Opioid Receptor Binding with [11C]Carfentanil: Evaluation of Reference-Tissue Approaches
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
6. A New Linear Parametric Imaging Algorithm Derived from a Simplified Reference Tissue Model for Ligand-Receptor Dynamic PET Studies
I. Introduction
II. Materials and Methods
III. Results and Discussion
7. PET Functional Parametric Images of Acetylcholine Esterase Activity without Blood Sampling
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
8. Reference-Tissue-Based Kinetic Analysis of [11C]MP4A PET Data without Arterial Input
I. Introduction
II. Materials and Methods
III. Results and Discussion
9. Pixel-by-Pixel Mapping of Acetylcholinesterase Activity in Human Brain with [11C]MP4A/PET
I. Introduction
II. Materials and Methods
III. Results and Discussion
10. Scatchard Analysis with Bolus/Infusion Administration of [11C]Raclopride: Amphetamine Effects in Anesthetized Monkeys
I. Introduction
II. Methods
III. Results
IV. Discussion
11. Comparison between Bolus and Infusion [11C]Raclopride Delivery for the Quantification of Dopamine Release
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
12. Bolus Infusion of [11C]Raclopride: Whole Body Kinetics and Tissue Uptake Error Estimates in Primate
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
13. Computationally Efficient Algorithms for Determining Weighted Average and Gray Matter Cerebral Blood Flow in Heterogeneous Tissues by Positron Emission Tomography
I. Introduction
II. Theory
III. Simulation Studies
IV. Results
I. Discussion
14. Bayesian Estimation of Kinetic Rate Constants Using PET and Compartmental Models
I. Introduction
II. Materials and Methods
III. Results and Discussion
15. Wavelet Methods for the Mathematical and Statistical Modeling of PET Images
I. Introduction
II. Methodology
III. Results
IV. Discussion
16. Use of MM Algorithm for Regularization of Parametric Images in Dynamic PET
I. Introduction
II. Theory
III. Methods
IV. Results
V. Discussion
VI. Conclusion
17. Tracer Kinetic Modeling via Basis Pursuit
I. Introduction
II. Materials and Methods
III. Results and Discussion
Part III Image Analysis
18. Measurement of Partial Volume Effect in the Ventral Striatum Using [11C]Raclopride
I. Introduction
II. Methods
III. Results
IV. Discussion
V. Conclusion
19. Volume-of-Interest-Based Automated Partial Volume Correction for Large Numbers of PET Data Sets
I. Introduction
II. Subjects Methods
III. Results
IV. Discussion
V. Conclusion
VI. Appendix
20. Parametric Definition of ROIs to Recover the Caliber of Cerebral Blood Vessels Directly from PET Images
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
21. A New Method of Selectively Analyzing Gray- or White-Matter Uptake in Brain PET Images
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
22. Partial Volume Correction of Simulated PET and 18F FDG PET from 14 Normal Brains
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
23. A Simple Approach to Combined Inhomogenity Correction and Tissue Segmentation of MR MPRAGE Images
I. Introduction
II. Materials and Methods
III. Results
IV. Conclusion
V. Further Development
24. Improved Lesion Localization in PET Using Cluster Analysis
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
25. Brain Tissue Clustering Based on Parametric Analysis
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
26. Methodological Aspects of [18F]FDG Regional Metabolic Covariance Pattern Comparisons in a Longitudinal PD Clinical Study
I. Introduction
II. Methods
III. Results
IV. Discussion
27. Is a FDG Template Applicable to Standardization of CBF Images in a 3D SSP System?
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
28. Comparison of FDG Normal Brain Images among Three PET Centers
I. Background and Purpose
II. Methods
III. Results
IV. Discussion
V. Conclusion
29. An MR-Based Statistical Volumetric Atlas of the Brain of Goettingen Miniature Pigs
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
30. Shortening rCBF Measurement Interval in [15O] H2O PET
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
Part IV Tracers and Basic Neuroscience
31. Animal PET for Brain Research From Receptor Binding to Second Messenger System
I. Introduction
II. Materials and Methods
III. Results
32. NK1 Receptor Occupancy in the Monkey Brain Studied by [11C]GR205171
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
33. Restoration of [18F]Fluorodopa Uptake in Brain of MPTP-Intoxicated Pigs with Fetal Mesencephalic Neuron Grafts
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
34. Mapping of Carbonic Anhydrase and Estrone Sulfatase in Rat Brain using 16a-[18F]Fluoroestradiol-3,17ss-disulfamate ([18F]FESDS)
I. Introduction
II. Methods
III. Results
IV. Discussion
35. In Vivo FWIN Uptake Correlates with In Vitro Measurements of the Dopamine Reuptake Transporter following MPTP Lesioning
I. Introduction
II. Materials and Methods
III. Results and Discussion
36. Mapping of the Sigma1 Receptors in the Primate Brain by PET with [11C]SA4503
I. Introduction
II. Materials and Methods
III. Results and Discussion
Part V Clinical Neuroscience and Mapping
37. Thalamic Stimulation for Parkinsonian Tremor: Correlation between Regional Cerebral Blood Flow and Biodynamic Tremor Characteristics
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
38. Brain Regions Involved in Learning Face-Name Associations and the Effects of Agem Performance, and Learning Phase
I. Introduction
II. Subjects and Methods
III. Results
IV. Discussion
39. Development of a PET System for Cognitive Activation Studies in Conscious Monkeys
I. Introduction
II. Materials and Methods
III. Results and Discussion
IV. Conclusion
40. Detection of Stage II Compromised Cerebrovascular Reserve by Xenon-CT Cerebral Blood Flow with Acetazolamide and Oxygen Extraction Fraction by Positron Emission Tomography
I. Introduction
II. Subjects and Methods
III. Results
IV. Discussion
41. Brain Mapping of Muscle-Brain Interaction during Chewing by SPM Analysis: A FDG-PET Study
I. Introduction
II. Methods
III. Results
IV. Discussion
42. Comparison of Mapping Parameters in [18F]FPCIT Imaging of Early Stage Parkinson's Disease
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
43. Comparative Analysis of Striatal FDOPA Uptake in Parkinson's Disease: SOR versus K1
I. Introduction
II. Materials and Methods
III. Results and Discussion
IV. Summary
44. Patterns of Distribution of [18F]6-Fluoro-L-rn-Tyrosine in PET Images of Patients with Movement Disorders
I. Introduction
II. Materials and Methods
III. Results
IV. Discussion
V. Conclusion
45. Comparison of Regional Cerebral Blood Flow Values between Xenon-133 and O-15 H2O PET Parametric Images
I. Introduction
II. Methods
III. Results and Discussion
46. Clinical Evaluation of a New Noninvasive Regional Cerebral Blood Flow Measurement Technique Using the Brain Uptake Ratio of 99mTc-ECD
I. Introduction
II. Materials and Methods
III. Results and Discussion
47. Statistical Mapping of the Brain Stem Using [18F]FDOPA PET Images: A Basic Study
I. Introduction
II. Methods
III. Results and Discussion
IV. Conclusion
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