Cytokines and autoimmune diseases
著者
書誌事項
Cytokines and autoimmune diseases
Humana Press, c2002
大学図書館所蔵 全4件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.
目次
Part I. Cytokines: Induction and Regulation
Transcriptional Regulation of Cytokine Gene Expression in The Subsets
Jyothi Rengarajan and Laurie H. Glimcher
Chromatin Remodeling and Transcriptional Regulation of Cytokine Gene Expression in T Cells
M. Frances Shannon and Adele F. Holloway
Variant Ligands, Altered T Cell Receptor Signaling, Hierarchial Response Thresholds, and CD4+ Effector Responses
Yasushi Itoh and Ronald N. Germain
The Role of Costimulation in T Cell Differentiation
Janet E. Buhlmann and Arlene H. Sharpe
CD1d-Restricted NK T Cells and Autoimmunity
Mark Exley and S. Brian Wilson
Role of T Cell Death and Cytokines in Autoimmunity
Luk Van Parijs and Abul K. Abbas
Role of Chemokines and Their Receptors in the Induction and Regulation of Autoimmune Disease
Richard M. Ransohoff and William J. Karpus
Part II. Cytokines: Role in Specific Autoimmune Diseases
Cytokines and Resistance to Organ Specific Autoimmune Disease
Benjamin M. Segal and Ethan M. Shevach
The Role of Cytokines in Induction and Regulation of Autoimmune Uveitis
Rachel R. Caspi
Pathogenic and Regulatory Cytokines in Experimental Autoimmune Encephalomyelitis
Estelle Bettelli and Lindsay B. Nicholson
Role of Cytokines in Multiple Sclerosis and Mucosal Tolerance
Howard L. Weiner
Cytokines and Human Type 1 Diabetes
Sally C. Kent, Vissia Viglietta, and David A. Hafler
Cytokines in Human Rheumatoid Arthritis and Murine Models
Marie Wahren-Herlenius, Helena Erlandsson Harris, Per Larsson, and Lars Klareskog
Systemic Lupus Erythematosus
Amy E. Wandstrat and Edward K. Wakeland
Myasthenia Gravis
Premkumar Christadoss and Elzbieta Goluszko
Part III. Cytokines and Autoimmunity: A Synthesis
Cytokines in Autoimmune Disease
Vijay K. Kuchroo and Lindsay B. Nicholson
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