BrainChip for biochemistry

著者

    • Lee, Scott
    • Turner, Michael
    • Lee, Grant

書誌事項

BrainChip for biochemistry

by Scott Lee, Michael Turner, Grant Lee

Blackwell Science, c2002

  • pbk.

タイトル別名

Brain chip for biochemistry

大学図書館所蔵 件 / 全2件

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内容説明・目次

内容説明

Just the book you have been looking for! BrainChip for Biochemistry is your guide to understanding the complexities of biochem. Blending clinical cases with concepts, this essential book brings together the basic science and clinical medicine you need for USMLE Step 1 review. * Written by students who know what you need* Trigger words that you need to know for the USMLE are bolded* Extensive diagrams and tables explain concepts* High-yield information -- your key for fast review for USMLE! Conquer the concepts of biochemistry with BrainChip! Look for these other books in the BrainChip Series! BrainChip for MicrobiologyBrainChip for Pathology

目次

1- General principles of biochemistry a. enzyme inhibition vs. stimulation b. enzyme activation vs. deactivation c. receptor up-regulation vs. down-regulation d. upstream vs. downstream e. rate-limiting step f. oxidation vs. reduction g. kinase vs. phosphotase enzyme actions h. synthesis vs. degradation of cAMP 2- Acid-Base-FUNdamental concepts a. equilibrium b. acids and their conjugate bases c. pH d. buffers e. carbonic acid/bicarbonate buffering system f. clinical correlation: response to acidosis and alkalosis 3- DNA and RNA- structure and important processes a. nitrogenous bases b. nucleotides c. DNA structure d. RNA structure e. replication f. transcription g. regulation of transcription h. translation i. summary comparison of replication, transcription, and translation j. types of DNA mutations 4- Techniques of Biotechnology and Molecular Biology a. procedures involving DNA and RNA b. procedures involving proteins 5- Proteins-- packaging, distribution, and functions in body a. structure b. packaging and distribution c. physiologically important proteins and their roles d. collagen, Vit C and scurvy e. porphyrinsf. hemeg. myoglobin h. hemoglobin i. metmyogobin and methemoglobin 6- Enzymes a. free energy b. properties of enzymes c. mechanism of action of enzymes d. Michaelis-Menten equation and Km e. allosteric enzymes and cooperative binding f. regulation of reaction velocity g. competitive vs. noncompetitive inhibition h. summary of reaction regulation strategies 7- Cellular Second Messenger Systems a. overview of 5 most important 2nd messenger systems b. detailed summary of 5 most important 2nd messenger systems c. summary of G protein-linked systems 8- Overview and Integration of Metabolisma. general principlesb. hormonal control of catabolismc hormonal control of anabolismd metabolic states: absorptive, post-absorptive, starvatione. roles of citratef. fates of pyruvateg. fates of Acetyl CoAh. glucose metabolismi. Insulinj Glucagon k. functions of the liver l. metabolic roles of the brain 9- The TCA cycle and the electron transport chain (ETC) a. functions of the TCA cycle b. reactants and products of the TCA cycle c. important ezymes of the TCA cycle d. stimulation and inhibition of the TCA cycle e. the logic of the electron transport chain f. electron transport chain complexes-key facts g. malate/aspartate shuttle h. glycerol-3-phosphate shuttle i. adenine nucleotide and phosphate carriers j. inhibitors of the ETC 10- Carbohydrate metabolisma. glycogen synthesisb. glycogen degradationc. glycogen storage diseasesd. metabolism of fructosee. metabolism of galactosef. metabolism of glucoseg. glycolysish. gluconeogenesisi. summary: the effects of insulin and glucagon on glycolysis and gluconeogenesisj. summary: key substances and relationships in carbohydrate metabolism 1. citrate 2. pyruvate 3. lactate 4. AcetylCoA 5. the Cori cycle 6. the glucose/alanine cycle k. ketone metabolisml. diabetes 11- lipid and cholesterol metabolism a.general principles b. fatty acid synthesis c. fatty acis degradation d. triglyceride synthesis e. triglyceride degradation f. triglyceride transport using lipoproteins g. phospholipids h. bile i. bilirubin j. cholesterol-synthesis and functions k. cholesterol transport using lipoproteins l. summary of apoproteins involved in fat and cholesterol transport m. summary of lipoproteins involved in fat and cholesterol transport n. integrated summary of fat and cholesterol transport o. steroid hormone synthesis 12- Protein and Nitrogen metabolism a. general principles b. amino acids: ketogenic, glucogenic, essential, non-essential c. transamination d. oxidative deamination e. the glutamate/glutamine cycle f. the glucose/alanine cycle g. ammonia metabolism h. homeostasis of amino acid levels g. the urea cycle 13 - Nucleotide Metabolism a. general principles b. The HMP shunt c. de nuovo purine synthesis d. purine synthesis by salvage pathway e. purine degradation f. de nuovo pyrimidine synthesis g. pyrimidine synthesis by salvage pathway h. pyrimidine degradation 14 - Integrated review of metabolism a. intracellular locations of metabolic reactions b. NAD+ -- what you need to know c. NADPH -- what you need to know d. citrate e. pyruvate f. lactate g. Acetyl CoA h. summary of important metabolic enzymes i. summary of "shuttle" systems used in metabolic reactions j. summary of 3 important metabolic cycles k. metabolic consequences of low carbohydrate intake l. biochemical rationales in favor of low-carb diets m. biochemical rationales against low-carb diets 15 - Nutrition a. overview of key concepts b. explanation of RDA c.water soluble vitamins d. fat soluble vitamins e. minerals f. deficiency symptoms g. clinical vignettes

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