The macrophage
著者
書誌事項
The macrophage
Oxford University Press, 2002
2nd ed
- hbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The field of macrophage research has grown enormously since publication of the first edition of this book. The Macrophage, Second Edition provides a unique, comprehensive review of the current scientific knowledge of the multifaceted role of this important and intriguing cell in health and disease. In 16 chapters, written by experts in the field, it covers the basic biology and diverse functions of macrophages in specific diseases and the complex
interactions between macrophages and other cells. Ranging from their role in the defence against pathogens, their role as hosts for pathogens (including HIV), their complex roles in diseases such as arthritis and cancer, and their potential for use in novel gene therapy approaches to disease treatment, the book
gives an up to the minute account of active macrophage research.
The editors have included a broad range of topics that will appeal not only to immunologists and cell biologists but will also be of interest to those working in the specific disease areas covered.
目次
- 1. The biology of the macrophage
- 2. Molecular basis of macrophage activation: from gene expression to phenotypic diversity
- 3. Macrophages as antigen presenting cells: relationship to dendritic cells and use in vaccination studies
- 4. Macrophage-virus interactions
- 5. Macrophages in bacterial infection
- 6. Macrophages in parasitic infection
- 7. Macrophages and Alzheimer's Disease
- 8. Macrophages in autoimmunity and primary immunodeficiency
- 9. Macrophages in rheumatoid arthritis
- 10. Macrophages in wound healing
- 11. Macrophages in tumour biology
- 12. Macrophages in cardiovascular disease
- 13. Macrophages in the central nervous system
- 14. Macrophages in reproductive biology
- 15. Macrophages in gene therapy: cellular targets and gene delivery vehicles
- 16. Use of mathematical modelling to simulate and predict macrophage activity in diseased tissues
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