Biologic therapy of leukemia
著者
書誌事項
Biologic therapy of leukemia
(Contemporary hematology)
Humana Press, c2003
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Exciting new "biologic" therapies for treating leukemia are appearing so rapidly that clinicians often find it difficult to make informed decisions about their use when making patient treatment decisions. Biologic Therapy of Leukemia summarizes and reviews all the available data concerning these cutting-edge biologic therapies so that practicing clinicians can make the correct patient-care choices. Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.
目次
Part I: Immunotherapy
Human Leukemia-Derived Dendritic Cells as Tools for Therapy
David Claxton
The Graft vs Leukemia Effect
Brian J. Bolwell
Unconjugated Monoclonal Antibodies
Matt Kalaycio
Drug Immunoconjugate Therapy of Acute Myeloid Leukemia
Arthur E. Frankel, Bayard L. Powell, Eli Estey, and Martin S. Tallman
Radiolabeled Monoclonal Antibodies
John M. Burke and Joseph G. Jurcic
Part II: Cytokines
Interferons
Thomas Fischer
Interleukin-2 Treatment of Acute Leukemia
Peter Kabos and Gary J. Schiller
Part III: Targeted Therapeutics
Antisense Therapy
Stanley R. Frankel
Signal Transduction Inhibitors
Michael E. O'Dwyer and Brian J. Druker
P-Glycoprotein Inhibition in Acute Myeloid Leukemia
Thomas R. Chauncey
Targeting the Apoptotic Machinery as a Potential, Antileukemic Strategy
Benjamin M. F. Mow and Scott H. Kaufmann
Part IV: Differentiation Agents
Arsenicals: Past, Present, and Future
Chadi Nabhan and Martin S. Tallman
All-Trans-Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia
Pierre Fenaux and Laurent Degos
Part V: Gene Therapy
Gene Therapy
Paul J. Orchard and R. Scott McIvor
Index
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