Advances in male mediated developmental toxicity
著者
書誌事項
Advances in male mediated developmental toxicity
(Advances in experimental medicine and biology, v. 518)
Kluwer Academic/Plenum Publishers, c2003
大学図書館所蔵 全11件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
"... a Second International Conference on Male Mediated Developmental Toxicity ..."--Pref
Includes bibliographical references and indexes
内容説明・目次
内容説明
It is nearly a decade since the first Male Mediated Developmental Toxicity conference was held in Pittsburgh. The continuing public/scientific interest, growing amounts of animal data, introduction of innovative technologies, and increasing quantity of human epidemiological studies all suggest that male-mediated developmental toxicity is of major concern. A number of researchers concluded that a Second International Confer- ence on Male Mediated Developmental Toxicity was necessary. The ensuing volume is particularly timely because it impacts on areas of special emphasis in many countries, with respect to children's and reproductive health, as well as to basic molecular mecha- nisms of environmental insult, and genetic susceptibility and predisposition. The Programme and Local Organizing Committee, composed of Barbara Hales (Chair, McGill University), BernardRobaire (McGill University), Daniel G. Cyr (INRS/ Armand Frappier), Jacquetta M. Trasler (McGill University), Andrew F. Olshan (Uni- versity of North Carolina), Sally Perreault Damey (US EPA), Donald R. Mattison (March of Dimes), and Jan M.
Friedman (University of British Columbia), spent over two years identifying individuals who had made key contributions in this field over the past decade and planning various aspects of the meeting. The meeting was held in Montreal in June 2001. A total of 132 persons, coming from five continents and representing some 18countries, took an active role in the proceedings. The conference was considered by all attendees to be a rousing success. Important discussions were held in the four break-out sessions, with a preliminary set of recommendations for action being presented by each panel.
目次
- Preface. Sponsors. List of Participants. Gender-Specificity of Gamete Susceptibilities to Exposures. 1. Female-Specific Reproductive Toxicities Following Preconception Exposure to Xenobiotics
- J.B. Bishop. 2. Overview of Male Mediated Developmental Toxicity
- D. Anderson. Exposures and Effects: Occupational and Environmental. 3. Epidemiologic Evidence on Biological and Environmental Male Factors in Embryonic Loss
- J.P. Bonde, et al. 4. Mechanisms of Male Mediated Developmental Toxicity Induced by Lead
- E.K. Silbergeld, et al. 5. Paternal Exposure to Known Mutagens and Health of the Offspring: Ionizing Radiation and Tobacco Smoke
- D.A. Savitz. 6. FISH (Fluorescence In Situ Hybridization) to Detect Effects of Smoking, Caffeine, and Alcohol on Human Sperm Chromosomes
- W.A. Robbins. Markers of Sperm Damage and Germ Line Genotoxicity. 7. Sperm Nuclear DNA Damage in the Human
- D. Sakkas, et al. 8. The Human Spermtozoon: Not Waving but Drowning
- J.R. Aitken, D. Sawyer. 9. Model Systems for Studying Germ Cell Mutagens: From Flies to Mammals
- E.W. Vogel, M.J.M. Nivard. 10. Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci
- Y.E. Dubrova. 11. PAINT/DAPI Analysis of Mouse Zygotes to Detect Paternally Transmitted Chromosomal Aberrations
- F. Marchetti, A.J. Wyrobek. Exposures and Effects: Causes of Cancer Consequences of Treatment. 12. Paternal Occupation and Childhood Cancer
- A.F. Olshan, E. van Wijngaarten. 13. Radiation and Malformations in a Murine Model
- W.-U. Muller. 14. Mechanisms of Action of Cyclophosphamide asa Male-Mediated Developmental Toxicant
- B. Robaire, B.F. Hales. 15. Chromosome Abnormalities in Human Sperm
- R.H. Martin. Pregnancy Outcome. 16. Distinguishing Between Fertilization Failure and Early Pregnancy Loss When Identifying Male-Mediated Adverse Pregnancy Outcomes
- S.D. Perrault. 17. ICSI, Male Pronuclear Remodeling and Cell Cycle Checkpoints
- L. Hewitson, et al. 18. Increased Incidence of Malformations in the Offspring of Male Mice Prenatally Exposed to Synthetic Estrogens
- T. Nagao, et al. Strategies for Prevention. 19. Implications of Research in Male-Mediated Developmental Toxicity to Clinical Councellors, Regulators, and Occupational Safety Officers
- J.M. Friedman. 20. Restoration of Spermatogenesis after Exposure to Toxicants: Genetic Implications
- M.L. Meistrich, et al. Future Directions. 21. Epigenetics: Role of Germ Cell Imprinting
- M.S. Bartolomei. 22. Efficiency and Safety of Animal Cloning
- R. Yanagimachi. Workshop Reports. 23. Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion
- S.D. Perreault, et al. 24. Risk Assessment
- A.F. Olshan, et al. 25. Study Designs for the Assessment of Male Mediated Developmental Toxicity
- B.F. Hales, D.C. Cyr. 26. Translational Research in Male Mediated Developmental Toxicity
- J.M. Trasler. Author Index. Subject Index.
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