Antidotes for poisoning by paracetamol

著者

    • Meredith, T. J. (...Timothy John...)

書誌事項

Antidotes for poisoning by paracetamol

scientific editors, T.J. Meredith ... [et al.]

(IPCS/EC evaluation of antidotes series, vol.3)

Published by Cambridge University Press, 1995

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注記

Includes bibliographical references

"EUR 15693 EN"

内容説明・目次

内容説明

This book, the third in the series, reviews the use of antidotes to paracetamol poisoning. Paracetamol, or acetaminophen, is involved in a large proportion of all poisoning incidents. The introductory chapter discusses the management of paracetamol poisoning, including the factors influencing its toxicity, and compares the efficacy of, and indications for the use of, supportive care and specific antidotal therapy. The following chapters then discuss the two antidotes, methionine and N-acetylcysteine, in detail. Subjects covered include: physico-chemical properties of the antidotes; analytical methods; animal and volunteer studies; and the results of clinical studies. The indications, advised route, dosage and restrictions relating to each antidote are summarised at the end of each chapter.

目次

  • Preface
  • Abbreviations
  • 1. Overview of antidotal therapy for acute paracetamol poisoning
  • 2. Methionine
  • 3. N-Acetylcysteine.

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