Xenotransplantation
著者
書誌事項
Xenotransplantation
(Current topics in microbiology and immunology, 278)
Springer, c2003
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注記
Includes index
内容説明・目次
内容説明
Xenotransplantation could have an impact on at least three aspects of medicine. The first is as a means of overcoming a severe shortage of human donor organs for the treatment of organ failure. The second aspect relates to the possibility that a xenogeneic organ would not be susceptible to infection by a "human" virus and thus the xenograft might resist injury caused by such viruses. The third and, as of yet, unexplored aspect relates to a means of delivering genes for therapeutic purposes thus overcoming some of the limitations of "conventional" gene therapy.
目次
Genetic modification of xenografts.-Public health risks - patient versus society in an emerging field.-Cross-species infections.-Non-human primate herpesviruses: importance for xenotransplantation.-Understanding xenotransplantation risks from non-swine hepatitis E virus: cross-species infection and risk in xenotransplantation.-Molecular cloning and functions characterization of infectious PERV and development of diagnostic tests.-Xenotransplantation - Federal regulatory considerations.-Subject index
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