Ageless quest : one scientist's search for genes that prolong youth
Author(s)
Bibliographic Information
Ageless quest : one scientist's search for genes that prolong youth
Cold Spring Harbor Laboratory Press, c2003
Available at / 5 libraries
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Graduate School of Pharmaceutical Sciences, Pharmaceutical Sciences Library, University of Tokyo図書
491.358:A195810438761
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Note
Includes bibliographical references (p. 137-144) and index
Description and Table of Contents
Description
Ageless Quest is a personal, sometimes controversial, account of the pursuit of a genetic 'cure' for aging by an expert in the field. The author is the Novartis Professor of Biology at the Massachusetts Institute of Technology. Aging has always been regarded as a highly complex process with many degenerative changes leading to the cessation of life. But recent research has identified a relatively simple mechanism that governs the pace of aging. Lenny Guarente's Ageless Quest is a scientific detective story for the baby boom generation. It offers an insider's view of an area of potentially astonishing high reward-and equally high risk.
Table of Contents
Preface Chapter 1 Mid-life crisis Chapter 2 Getting started in aging Chapter 3 First genetic insight Chapter 4 Identification of the AGE locus Chapter 5 The rise and fall of rDNA circles and the emergence of SIR2 Chapter 6 A molecular blueprint for prolonging life span Chapter 7 SIR2 as a universal regulator of survival Chapter 8 Nature promotes survival in the face of scarcity Chapter 9 Theories of aging: SIR2 is more evolutionary than revolutionary Chapter 10 Calorie restriction and life span Chapter 11 Aging and cancer in mammals Chapter 12 Relevance to human aging Chapter 13 Starting a biotechnology company: Drugs for aging? Chapter 14 Aging gracefully in the 21st century Snapshots Bibliography Glossary Index
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