Angiotensin II receptor antagonists in perspective
著者
書誌事項
Angiotensin II receptor antagonists in perspective
Martin Dunitz, 2000
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Since angiotensin II is one of the most potent vasoconstrictors and an important stimulus for the secretion of aldosterone from the adrenal gland, the development of angiotensin II inhibitors is an important step in regulating blood pressure. This class of drug is well-tolerated by patients and these drugs have the added advantage over ACE inhibitors in that they are not associated with cough. Because most drugs can be given once daily and, like ACE inhibitors, they have a useful additive hypotensive effect in combination with diuretics, they are a welcome therapeutic tool in the treatment of hypertension.
目次
1. Introduction 2. Mechanisms of Action and Differences with Other Drugs Acting on Renin Angiotensin System (RAS) 3. Comparative Pharmacology 4. The Use of Angiotensin II Antagonists as Monotherapy in Hypertension 5. The Use of Angiotensin II Antagonists in Combination Treatment for Hypertension 6. Angiotensin II Antagonists and Hypertension of the Elderly (including Systolic Hypertension) 7. Angiotensin II Antagonists in Diabetic Hypertensives and other Special Hypertensive Groups 8. Organ Protective Properties of Angiotensin II Antagonists (including Animal Data with Clear Clinical Implications) 9. Angiotensin II Antagonists and Congestive Heart Failure 10. Ongoing Trials with Angiotensin II Antagonists
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