Phosphoinositides in subcellular targeting and enzyme activation
著者
書誌事項
Phosphoinositides in subcellular targeting and enzyme activation
(Current topics in microbiology and immunology, 282)
Springer, c2004
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注記
Includes index
内容説明・目次
内容説明
Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.
目次
Preface.- Phosphoinositide involvement in phagocytosis and phagosome maturation.- Regulation of endocytosis by phosphatidylinositol 4,5-biphosphate and ENTH proteins.- Membrane targeting by pleckstrin homology (PH) domains.- Protein targeting to endosomes and phagosomes via FYVE and PX domains.- Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in neutrophil function.- Nuclear phosphoinositides and their functions.- Subject index.
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