Phosphoinositides in subcellular targeting and enzyme activation

書誌事項

Phosphoinositides in subcellular targeting and enzyme activation

H. Stenmark (ed.)

(Current topics in microbiology and immunology, 282)

Springer, c2004

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注記

Includes index

内容説明・目次

内容説明

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

目次

Preface.- Phosphoinositide involvement in phagocytosis and phagosome maturation.- Regulation of endocytosis by phosphatidylinositol 4,5-biphosphate and ENTH proteins.- Membrane targeting by pleckstrin homology (PH) domains.- Protein targeting to endosomes and phagosomes via FYVE and PX domains.- Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in neutrophil function.- Nuclear phosphoinositides and their functions.- Subject index.

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  • Current topics in microbiology and immunology

    Springer-Verlag 1967-

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