Development of auditory and vestibular systems-3 : molecular development of the inner ear
Author(s)
Bibliographic Information
Development of auditory and vestibular systems-3 : molecular development of the inner ear
(Current topics in developmental biology / edited by A.A. Moscona, Alberto Monroy, v. 57)
Elsevier Academic Press, c2003
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.
Table of Contents
Molecular conservation and novelties in vertebrate ear development
Use of mouse genetics for studying inner ear development
Formation of the outer and middle ear, molecular mechanisms
Molecular basis of inner ear induction
FGF signaling in ear development and innervation
The roles of retinoic acid during inner ear development
Hair cell development in higher vertebrates
Growth factors and early development of otic neurons
The cell cycle and the development and the regeneration of hair cells
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