The microbial models of molecular biology : from genes to genomes

著者

書誌事項

The microbial models of molecular biology : from genes to genomes

Rowland H. Davis

Oxford University Press, 2003

大学図書館所蔵 件 / 全11件

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注記

Bibliography: p. 303-322

Includes index

内容説明・目次

内容説明

This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.

目次

1: Model systems, model organisms 2: Morgan's progeny 3: Neurospora 4: Aspergillus 5: Yeast 6: Leaving the fungi 7: Escherichia coli 8: The T bacteriophages 9: Temperate phage and transduction 10: DNA 11: Prokaryotes take center stage 12: Prokaryotes: Later contributions 13: Cytoplasmic inheritance: The ciliates 14: Organelle genetics: Yeast and Chlamydomonas 15: Yeast becomes a supermodel 16: The Filamentous fungi: Eclipse and renewal 17: The role of biochemistry 18: Genomics 19: The age of model organisms Appendix 1. Life cycles and genetic principles Appendix 2. Macromolecules and the Central Dogma Appendix 3. Genetic engineering Notes References Name index Subject index

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