Parkinson's disease : diagnosis and clinical management

著者

書誌事項

Parkinson's disease : diagnosis and clinical management

Stewart A. Factor, William J. Weiner, editors

Demos, c2002

  • : hardcover

大学図書館所蔵 件 / 全2件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Parkinson's disease (PD) is the second most common neurodegenerative disease. As the population of the industrialized world ages the impact of this disease on clinical neurology will expand. The growing literature regarding PD reflects this phenomenon. The time is now appropriate for a comprehensive text on PD that provides the reader with an up-to-date review on the multiple aspects of the disease and puts them into perspective. The scholarly contributions from many of the leading researchers in the field has made such a text a reality. This book will be useful to movement disorder specialists, general neurologists and neurology residents, gerontologists, neurosurgeons, neuropsychologists, and neuroscience researchers. The text provides both theoretical and practical approaches to PD.

目次

  • History. James Parkinson: The man and the Essay
  • Paralysis Agitans in the 19th Century
  • Charcot and Parkinson's disease
  • Parkinson's Disease in the 20th century: A time line of important events. Clinical Aspects: Epidemiology
  • Cardinal features of early disease
  • The gait disturbances in PD
  • Sensory symptoms
  • Speech, Voice and Swallowing Disorders
  • Gastrointestinal features
  • Autonomic Nervous System dysfunction
  • Sleep Disorders
  • Natural History
  • Quantitative measures / Rating scales. Behavioral and Psychiatric Manifestations: Dementia
  • Dementia with Lewy bodies and Alzheimer's disease and their relationship to PD
  • Depression
  • Anxiety and Panic disorder
  • Apathy and the motivational state. Pathology and Neurochemistry: Pathology
  • Neurochemistry
  • Basal Ganglia Anatomy & Physiology
  • Dopamine receptor Diversity. Diagnosis: Problems in Diagnosis
  • Positron emission tomography
  • Single photon emission tomography and Dopamine transporter imaging. Etiology and Pathogenesis: Etiology: The roles of environment and genetics
  • Pathogenesis: Oxidative stress, mitochondrial dysfunction and excitotoxicity
  • Apoptosis
  • The impact of MPTP on Parkinson's Disease research: past, present and future
  • Cerebrospinal Fluid neurotoxicity: clues to pathogenesis. Drugs: Levodopa: 30 years of progress
  • Amantadine and Anticholinergics
  • Monoamine oxidase inhibitors
  • Dopamine Agonists
  • COMT inhibitors
  • Atypical Antipsychotics
  • Excitatory Amino Acid receptor antagonists
  • Other therapies. Treatment Issues: Motor Fluctuations and Dyskinesia
  • Fluctuations of non-motor symptoms
  • Psychosis
  • Status on Protective therapies
  • Treatment approaches for Early Disease
  • Progress in Gene therapy
  • Neurotrophic Factors
  • Smoking and Nicotine. Surgery: Stereotactic Pallidotomy & Thalamotomy
  • Thalamic Stimulation
  • Pallidal and Subthalamic stimulation
  • Neural transplantation. Subtypes of Parkinsonism: Juvenile and Young onset Parkinsonism
  • Is there a Familial form?
  • The Parkinson-Plus Syndromes
  • Symptomatic Parkinsonism. Social Issues: Quality of Life Issues
  • Family Caregiving
  • Economic impact: Implications for Interventions
  • Driving.

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