Metabolic engineering in the post genomic era
著者
書誌事項
Metabolic engineering in the post genomic era
Horizon Bioscience, c2004
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The book brings together all the recent, most important breakthroughs in this exciting field. Internationally renowned key scientists have reviewed each topic in detail. In the Introduction, the editors give an overview of new approaches and spell out what the engineer and the industry may now really begin to aim for; they even adapt the definition of metabolic engineering to befit the post-genomics era.
目次
Introduction. 1. Metabolic Engineering, What it Was and What it is. Analytical Tools. 2. Proteomics in Metabolic Engineering. 3. Magnetic Resonance Spectroscopy and Imaging - Powerful Tools for Functional Genomics. 4. Metabolic Flux Analysis in the Post Genomics Era. 5. Regulatory Strength Analysis for Inferring Gene Networks. Engineering Tools. 6. The MetaCyc Metabolic Pathway Database. 7. Experimental Modulation of Gene Expression. Modeling Methodology. 8. Metabolic Pathway Analysis in Biotechnology. 9. In Silico Cells: Studying Genotype-Phenotype Relationships Using Constraints-Based Models. 10. A Multi-scale Approach for the Predictive Modeling of Metabolic Regulation. 11. Validation of Metabolic Models: Concepts, Tools, and Problems. Examples of Applications. 12. Applications of Whole Cell and Large Pathway Mathematical Models in the Pharmaceutical Industry. 13. Metabolic Engineering of Branched Systems: Redirecting the Main Pathway Flux. 14. Redirecting Metabolism by Co-ordinate Manipulation of Multiple Genes. 15. Metabolic Engineering and Flux Analysis of Glycine Betaine Synthesis in Plants: Progress and Prospects. Perspectives. 16. Metabolic Engineering in the Post Genomic Era: What it Should Become.
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