Helicobacter pylori infection : new facts, new views
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Bibliographic Information
Helicobacter pylori infection : new facts, new views
（Digestive diseases, v. 19,
Karger, c2001
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Includes bibliographical references and indexes
Description and Table of Contents
Description
The discovery of Helicobacter pylori in the 1980ies has revolutionized the management of peptic ulcer disease, the most recent development being a vaccine against the bacterium. Nevertheless, strategies for the targeting and management of H. pylori are constantly developed further as several H. pylori associated clinical conditions remain an issue of debate and controversy. Research on the basic mechanisms of the infection is also continuing, and new findings and challenging views are continuously emerging, without providing definitive answers yet. This publication presents new facts useful for the clinician, addressing questions such as the contribution of bacterial virulence and genetic predisposition of the host to disease outcomes. It is also a puzzle why a smaller group of H. pylori infected patients develops clinical manifestations, but a much larger proportion remains asymptomatic. It is also discussed how to deal with the dyspeptic patient in primary care, whether H. pylori eradication for functional dyspepsia should be recommended in the specialist setting and the intriguing relationship between H. pylori and gastroesophageal reflux disease. Providing an overview of the current state of diagnostic and therapeutic standards and discussing the possible implementation of probiotics as well as the hope for novel therapies connected with the new vaccine, this publication is aimed at the clinician faced with patients suffering from H. pylori infection.
Table of Contents
- Impact of Helicobacter pylori virulence on the outcome of gastroduodenal diseases - lessons from the microbiologist, Francis Megraud
- Helicobacter pylori infection as a model for gastrointestinal immunity and chronic inflammatory diseases, Peter B. Ernst, Hiromasa Takaishi, Sheila E. Crowe
- new Helicobacter species in humans, Leif Percival Andersen
- current standards in the diagnosis of Helicobacter pylori infection, A. Leodolter, K. Wolle, P. Malfertheiner
- impact of H. pylori infection on the management of dyspepsia, T. Rokkas
- Helicobacter pylori - a debated factor in gastroesophageal reflux disease, Prateek Sharma
- Helicobacter pylori therapy - first-line options and rescue regimen, Javier P. Gisbert, J.M. Pajares
- Helicobacter pylori treatment - a role for probiotics?, Filippo Cremonini, Filippo Canducci, Simona Di Caro, et al
- vaccines - an ongoing promise?, Mazen Alsahli, Richard J. Farrell, Pierre Michetti
- diffusion of knowledge about Helicobacter pylori as assessed in an open-access endoscopy system - a prospective observational study based on the Maastricht guidelines, Gianpiero Manes, Sandro Mosca, Antonio Balzano, et al
- the prevalence of Helicobacter pylori infection and the pattern of gastritis in Barrett's esophagus, Ulrich Peitz, Andreas Hackelsberger, Thomas Gunther et al
- H. pylori infection and visceral hypersensitivity in patients with irritable bowel syndrome, C. Gerards, A. Leodolter, B. Glasbrenner, P. Malfertheiner
- a randomized trial of lansoprazole, amoxycillin, and clarithromycin versus lansoprazole, bismuth, metronidazole and tetracycline in the retreatment of patients failing initial Helicobacter pylori therapy, Nathan Magaret, Michael Burm, Douglas Faigel, et al
- resolution of Menetrier's disease after Helicobacter pylori eradicating therapy, Giuseppe Di Vita, Rosalia Patti, Federico Aragona, et al.
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