Alkaloids : chemical and biological perspectives
Author(s)
Bibliographic Information
Alkaloids : chemical and biological perspectives
Elsevier, 1998
- v. 12
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
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  Gunma
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  Fukui
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  Nagano
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  Kyoto
  Osaka
  Hyogo
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  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
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  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
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  Okinawa
  Korea
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  United Kingdom
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Note
Includes index
Description and Table of Contents
Description
Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, Acronychia baueri Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties.
Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work.
Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.
Table of Contents
Acronycine-type alkaloids: chemistry and biology (F. Tillequin et al.). Solanum steroid alkaloids - an update (H. Ripperger). Synthesis and structure-activity studies of Lissoclinum peptide alkaloids (P. Wipf). Pyroglutamate as a chiral template for the synthesis of alkaloids (M.B. Smith). Analysis of alkaloids by capillary electrophoresis and capillary electrophoresis - electrospray mass spectrometry (J. Stoeckigt et al.). Oxidation of anthelmentic marcofortine A, an indole alkaloid (B.H. Lee et al.). Subject index. Organism index.
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