The organic chemistry of drug design and drug action

Author(s)
    • Silverman, Richard B.
Bibliographic Information

The organic chemistry of drug design and drug action

Richard B. Silverman

Elsevier Academic Press, 2004

2nd ed

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction.

Table of Contents

1. Introduction 2. Drug Discovery, Design, and Development 3. Receptors 4. Enzymes (Catalytic Receptors) 5. Enzyme Inhibition and Inactivation 6. DNA-Interactive Agents 7. Drug Metabolism 8. Prodrugs and Drug Delivery Systems

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