The organic chemistry of drug design and drug action
著者
書誌事項
The organic chemistry of drug design and drug action
Elsevier Academic Press, 2004
2nd ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction.
目次
1. Introduction
2. Drug Discovery, Design, and Development
3. Receptors
4. Enzymes (Catalytic Receptors)
5. Enzyme Inhibition and Inactivation
6. DNA-Interactive Agents
7. Drug Metabolism
8. Prodrugs and Drug Delivery Systems
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