Molecular biology and immunology in hepatology : advances in the treatment of intractable liver diseases

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書誌事項

Molecular biology and immunology in hepatology : advances in the treatment of intractable liver diseases

edited by Takao Tsuji ... [et al.]

Elsevier, 2002

大学図書館所蔵 件 / 全3件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book presents an integration of recent knowledge of virology, molecular biology and immunology focusing on intractable liver diseases. It reports on mechanisms of liver injury e.g. viral hepatitis, fulminant hepatic failure, autoimmune hepatitis, and hepatocarcinogenesis based on the evidence from both clinical and basic research e.g. genetic diversities or transgenic mice models. It also explains current concepts and new strategies to treat alcoholic liver diseases, interferon resistant hepatitis C virus, liver cirrhosis, fulminant hepatic failure, and hepatocellular carcinoma e.g. new drugs, immunotherapy, gene therapy or living related liver transplantation. The authors are all front runners in current hepatology and give us proper information on each topic. The book will be of interest to all clinicians and basic scientists devoted to hepatology and will be a useful guide to reveal what we can do now and what we should do to treat intractable liver diseases.

目次

Hepatology in 21st century. General Aspects of Molecular Biology and Immunology for the Treatment of Intractable Liver Diseases (K.-H. Meyer zum Buschenfelde). Viral Hepatitis. The Mechanisms of Liver Injury in Hepatitis B Virus Infection (T. Ishikawa, S. Kakumu). Genetic Diversity and Pathophysiology of Hepatitis B Virus (H. Yatsuhashi, M. Yano). Immunopathogenesis of Hepatitis C (M.J. Koziel). Recent Advancement in Interferon Therapy for Hepatitis C Treatment (J. Feher, G. Lengyel). New Therapeutic Strategy for Chronic Hepatitis C (N. Hayashi, A. Kasahara). Transgenic Mouse Models for Viral Hepatitis: The Role of Hepatitis Viruses in Hepatocarcinogenesis (K. Koike). Gene Therapy of Viral Hepatitis (H.E. Blum). Liver Cirrhosis. Reversibility of Liver Cirrhosis: Evidence from Clinical and Basic Research (A. Watanabe). Hepatocellular Carcinoma. Treatment of Hepatocellular Carcinoma: Diverse Strategies Based on Underlying Liver Diseases (M. Omata). Gene Expression Profiles in Hepatocellular Carcinoma (S. Kaneko, K. Kobayashi). Gene Therapy for Hepatocellular Carcinoma: Recent Advancements and Problems to Overcome (S. Kuriyama, H. Tsujinoue, T. Nakatani, H. Yoshiji, H. Fukui). Novel Immunological Approach for the Treatment of Hepatocellular Carcinoma (T. Higashi, K. Nouso, M. Uemura, S.J. Nakamara, Y. Kobayashi). Alcoholic Liver Injury. Assessment of the Reversibility and Treatments of Alcoholic Liver Disease (J.C. Bode). Autoimmune Liver Diseases. Molecular Mechanisms of Autoimmune Hepatitis (A. Vogel, M.P. Manns). Roles of Hepatitis C Virus Infection in Autoimmune Hepatitis (H. Miyakawa). Molecular Mechanisms of T-cell Responses of Autoimmune Hepatitis (M. Zeniya, H. Takahashi, Y. Aizawa, G. Toda). Primary Biliary Cirrhosis: Solving the Enigma (K. Yamamoto, M.E. Gershwin). Induction of T cell Anergy by Peptide Analogue in Primary Biliary Cirrhosis (H. Ishibashi, S. Shimoda, H. Shigematsu, M. Nakamura). Putative Mechanism of Overlap Syndrome: What is the Entity? (S. Onji, K. Yamamoto). Fulminant Hepatic Failure. Etiology and Pathophysiology of Fulminant Hepatic Failure (K. Fujiwara, S. Mochida). Cytokines and Fulminant Hepatic Failure (K. Kayano, I. Sakaida, K. Okita). Treatment and Prognosis of Fulminant Hepatic Failure (M. Yoshiba). Living Related Liver Transplantation. Current Strategy of Living Related Liver Transplantation: Overview (K. Tanaka, S. Kaihara). Viral Cirrhosis and Hepatocellular Carcinoma in Relation to Living-Donor Liver Transplants (T. Ichida). Subject Index.

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