書誌事項

Drug delivery systems

Vasant V. Ranade, Mannfred A. Hollinger

(Pharmacology & toxicology)

CRC Press, c2004

2nd ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both industry and academia. New in this edition: Chapter focusing on novel technologies and their global outlook Coverage of electronically controlled drug delivery Macrocapsules and nanoparticles in drug targeting Drug nanocrystals and other new delivery systems Updated information on liposomes as carriers Written in a straightforward, clear, and concise manner, the author provides a global perspective on current and future advances and market opportunities. Drug Delivery Systems, Second Edition answers the need for comprehensive information in a single resource for anyone venturing into this area of drug development.

目次

SITE-SPECIFIC DRUG DELIVERY Site-Specific Drug Delivery Using Liposomes as Carriers Introduction Liposomes in Drug Delivery The Liposome-Drug Concept Liposomes as Carriers of Therapeutic Agents Recent Advances Concluding Remarks Site Specific Drug Delivery Utilizing Monoclonal Antibodies Introduction Production of Monoclonal Antibodies Drug-Monoclonal Antibody Conjugates for Drug Targeting Recent Studies with Monoclonal Antibodies Conclusion and Basis for Future Trends References POLYMERS, IMPLANTABLE DRUG DELIVERY Role of Polymers in Drug Delivery Introduction Currently Available Polymers Soluble Polymers Biodegradable or Bioerodible Polymers Mucoadhesive Polymers Polymers Containing Pendant Substituents Matrix Systems Heparin Releasing Polymers Ionic Polymers Oligomers Miscellaneous Recent Advances Conclusion Implants in Drug Delivery Introduction Insulin Delivery as a Model Implant Pump System Implants for Contraception ORAL DRUG DELIVERY Oral Drug Delivery Introduction Features of the GI Tract Targeting of Drugs in the GI Tract Design and Fabrication of Oral Delivery systems Survey of Oral Controlled Release Products Recent Advances Conclusion References TRANSDERMANL, INTRANASAL, OCULAR, AND MISCELLANEOUS DRUG DELIVERY Transdermal Drug Delivery Introduction Structure of Human Skin Theoretical Advantages of the Transdermal Route Optimization of Percutaneous Absorption Theory for Penetration-Enhancer Activity Development of the Transdermal Therapeutic System Examples of Transdermal Applications Transdermal Controlled-Release Products and Devices Recent Advances Conclusion References Intranasal and Ocular Drug Delivery Intranasal Drug Delivery Ocular Drug Delivery References Miscellaneous Forms of Drug Delivery Introduction Prodrugs Infusion Devices Insulin Delivery Parenteral Prolonged Action Dosage Forms Summary REGULATORY CONSIDERATIONS AND GLOBAL OUTLOOK Regulatory Considerations for Drug Delivery Systems Introduction Current Status of Drug Delivery Technology Submission of Documents for Manufacture and Quality Drug Delivery Industry and the Global Outlook INDEX

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