Biochemical targets of plant bioactive compounds : a pharmacological reference guide to sites of action and biological effects
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Bibliographic Information
Biochemical targets of plant bioactive compounds : a pharmacological reference guide to sites of action and biological effects
Taylor & Francis, 2003
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Note
Includes bibliographical references and index
Contents of Works
- Plant defensive compounds and their biochemical targets: Introduction
- Organization and scope of the book
- Description of the tables
- Using the tables
- The structural diversity of plant defensive compounds
- Plant alkaloids
- Plant phenolics
- Plant terpenes
- Other plant compounds
- Biochemistry: the chemistry of life
- Introduction: water-based life
- Protein structure
- Enzymes and ligand-binding proteins
- Metabolic strategies
- Inhibition of biochemical processes by plant defensive compounds
- Neurotransmitter- and hormone-gated ion channels
- Introduction: Electrical signalling in excitable cells
- Ionotropic neurotransmitter receptors - neurotransmitter-gated ion channels
- Structure and function of ionotropic receptors
- Nicotinic acetylcholine receptor agonists and antagonists
- Ionotropic (-aminobutyric acid and benzodiazepine receptors
- Ionotropic glutamate, glycine and serotonin receptors
- Sigma and vanilloid receptors
- Ion pumps and ligand- and voltage-gated ion channels
- Introduction: Ion pumps
- Voltage-gated na+ channels
- Ligand-regulated and voltage-gated k+ channels
- Voltage-gated ca2+ channels
- Ligand-gated ca2+ channels
- Chloride transport and voltage-regulated chloride channels
Description and Table of Contents
Description
When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents.
Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.
Table of Contents
Plant Defensive Compounds and Their Biochemical Targets. Biochemistry - The Chemistry of Life. Neurotransmitter and Hormone-gated Ion Channels. Ion Pumps and Ligand and Voltage-gated Ion Channels. Plasma Membrane G Protein-coupled Receptors. Neurotransmitter Transporters and Converters. Cyclic Nucleotide-, Ca2+ and Nitric Oxide-based Signaling. Signal-regulated Protein Kinases. Gene Expression, Cell Divisiona and Apoptosis. Taste and Smell Perception, Pheromones and Semiochemicals. Agonsists and Antagonists of Cystolic Hormone Receptors. Polynucleotides, Polysaccharides, Phospholipids and Membranes. Inhibitors of Digestion and Metabolism. Anti-inflammatory, Antioxidant and Antidiabetic Plant Compounds.
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