Antibiotics : actions, origins, resistance

Author(s)

• Walsh, Christopher

Bibliographic Information

Antibiotics : actions, origins, resistance

by Christopher Walsh

ASM Press, c2003

Note

Includes bibliographical references (p. 297-328) and index

Contents of Works

• Antibiotics : initial concepts
• Introduction to major antibiotic classes and modes of action
• Antibiotics that act on cell wall biosynthesis
• Antibiotics that block bacterial protein biosynthesis
• Antibiotics that block DNA replication and repair : the Quinolones
• Other targets of antibacterial drugs
• Natural and producer immunity versus acquired resistance
• Enzymatic destruction or modification of the antibiotic by resistant bacteria
• Antibiotic resistance by efflux pumps
• Antibiotic resistance by replacement or modification of the antibiotic target
• Regulation of antibiotic biosynthesis in producer organisms
• Polyketide antibiotic biosynthesis : assembly line enzymology
• Enzymatic assembly lines for nonribosomal peptide antibiotics
• Biosynthesis of other classes of antibiotics
• New looks at targets
• New molecules
• Contexts and challenges for the use of new antibiotics

Details

• NCID: BA65768708
• ISBN:
  • 1555812546
• Country Code: us
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Washington, D.C.
• Pages/Volumes: x, 335 p.
• Size: 26 cm
• Classification:
  • LCC : RM267
  • NLM : QV 350
  • DC21 : 615/.329
• Subject Headings:
  • LCSH : Antibiotics
  • LCSH : Drug resistance in microorganisms
  • MESH : Antibiotics -- pharmacology
  • MESH : Drug Resistance, Bacterial