Tissue restoration through regenerative biology and medicine

書誌事項

Tissue restoration through regenerative biology and medicine

D.L. Stocum

(Advances in anatomy, embryology and cell biology, 176)

Springer, c2004

  • pbk.

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注記

Includes bibliographical references (p. 77-101) and index

内容説明・目次

内容説明

Advances in cell, developmental and molecular biology, and the discovery of regeneration-competent cells in many non-regenerating mammalian tissues, have given impetus to systematic investigations that will enable us to regenerate these tissues by cell transplantation or the pharmaceutical induction of regeneration from the body's own tissues. A significant avenue of research is the identification of the soluble and insoluble signals and their transduction pathways that govern the proliferation and differentiation of regeneration-competent cells, and the signals that inhibit their activity after injury. How far can we go in our quest for regeneration? We will probably be able to induce the regeneration of some tissues, such as skin or even spinal cord, within a few years. The regeneration of others, such as heart, lung, kidney or appendages, may be more complex and difficult, but we should not view them as impossible. They will just take a little longer.

目次

Introduction.- The Biology of Regeneration.- Regeneration of Ectodermal Derivatives.- Regeneration of Endodermal Derivatives.- Regeneration of Mesodermal Derivatives.- Developmental Potential of Adult Stem Cells.- Regenerative medicines.- Cell Transplants.- Chemical Induction of Regeneration in vivo.- Perspectives.- Subject Index

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