Immunobiology : the immune system in health and disease

Bibliographic Information

Immunobiology : the immune system in health and disease

Charles A. Janeway, Jr. [et al.]

Garland Science, c2005

6th ed

  • Garland : pbk.
  • Churchil Livingstone : pbk.
  • Churchil Livingstone : pbk.

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Note

Includes bibliographical references and index

Description and Table of Contents

Volume

Churchil Livingstone : pbk. ISBN 9780443073106

Description

The central thesis of this book is that the immune system exists to protect the host from infection and that its evolutionary history was shaped by this challenge. Other aspects of immunology (for example allergy, graft rejection etc) are variations on the basic protective function. The first part of the book summarises the basic immunological concepts and introduces the main 'players'. The middle three parts deal with main aspects of adaptive immunity. The last part integrates the material at the level of the complete organism in both health and disease. A major feature of the book are the superb four-colour line drawings depicting the immunological processes. Each chapter ends with an extensive list of references and further reading. The book ends with a 20 page glossary. Unlike some of its competitors this book was written by just four main co-authors (although drawing on expert advice from many colleagues) and so has great consistency and cohesiveness.

Table of Contents

Part I: An introduction to immunobiology and innate immunity Basic concepts in immunology. Innate immunity. Part II: The recognition of antigen Antigen recognition by B and T cell receptors. The generation of Lymphocyte antigen receptors. Antigen presentation to T lymphocytes. Part III: The development of mature lymphocyte receptor repertoires Signaling through immune system receptors. The development and survival of lymphocytes. Part IV: The adaptive immune response T-cell mediated immunity. The humoral immune response. Adaptive immunity to infection. Part V: The immune system in health and disease Failure of host defense mechanisms. Allergy and hypersensitivityAutoimmunity and transplantation. Manipulation of the immune response. Part VI: Where the immune system came from and where is immunology going Evolution Appendices The immunologists' toolbox. List of current CDs. Cytokines and their receptors. Chemokines and their receptors.
Volume

Garland : pbk. ISBN 9780815341017

Description

Immunobiology, Sixth Edition guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The Sixth Edition has been thoroughly revised and updated, and now includes end-of-chapter questions. Immunobiology sets the standard for currency and authority with its clear writing style and organization, full-color art program, scientific accuracy, frequent updates, and consistent viewpoint - that of the host's interaction with an environment containing many species of potentially harmful microorganisms.

Table of Contents

1. Basic Concepts in Immunology 2. Innate Immunity 3. Antigen Recognition by B-cell and T-cell Receptors 4. The Generation of Lymphocyte Antigen Receptors 5. Antigen Presentation to T Lymphocytes 6. Signaling Through Immune System Receptors 7. The Development and Survival of Lymphocytes 8. T Cell-Mediated Immunity 9. The Humoral Immune Response 10. Adaptive Immunity to Infection 11. Failures of Host Defense Mechanisms 12. Allergy and Hypersensitivity 13. Autoimmunity and Transplantation 14. Manipulation of the Immune Response 15. Evolution of the Innate Immune System

by "Nielsen BookData"

Details

  • NCID
    BA67889179
  • ISBN
    • 0815341016
    • 0443073104
    • 0443073090
  • LCCN
    2004007144
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    New York
  • Pages/Volumes
    xxiii, 823p.
  • Size
    28cm
  • Attached Material
    1 CD-ROM
  • Classification
  • Subject Headings
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