Microbial genomes
著者
書誌事項
Microbial genomes
(Infectious disease)
Humana Press, c2004
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.
目次
Part I: Introduction
History of Microbial Genomics
Hamilton O. Smith
Part II: Bioinformatics As a Tool in Genomics
Tools for Gene Finding and Whole Genome Comparison
Steven L. Salzberg and Arthur L. Delcher
Bacterial Genome Annotation at TIGR
Owen White
Bioinformatics and Microbial Pathogenesis
Fiona S. L. Brinkman and Joanna L. Fueyo
Bacteriophage Bioinformatics
Derrick E. Fouts
Part III: Core Functions
Comparative Microbial Metabolism
Karen E. Nelson
Genomic Analysis of Membrane Transport
Ian T. Paulsen, Katherine H. Kang, Mark E. Hance, and Qinghu Ren
Genomics-Based Analysis of the Bacterial Cell Cycle
Michael T. Laub, Harley H. McAdams, and Lucy Shapiro
Part IV: The Evolution of Microbial Genomes
A Brief History of Views of Prokaryotic Evolution and Taxonomy
Lorraine Olendzenski, Olga Zhaxybayeva, and J. Peter Gogarten
How Bacterial Genomes Change
Timothy D. Read and Garry S. A. Myers
Concepts of Bacterial Biodiversity for the Age of Genomics
Frederick M. Cohan
Coevolution of Symbionts and Pathogens With Their Hosts
Robert A. Feldman
Part V: A Survey of Microbial Genome
A Survey of Plant Pathogen Genomes
C. Robin Buell
Anoxygenic Phototrophic Bacteria
F. Robert Tabita and Thomas E. Hanson
Genomics of Thermophiles
Frank T. Robb
The Genomes of Pathogenic Enterobacteria
Julian Parkhill and Nicholas R. Thomson
Obligate Intracellular Pathogens
Siv G. E. Andersson
Low G+C Gram-Positive Genomes
Steven R. Gill
Genomics of Actinobacteria, the High G+C Gram-Positive Bacteria
Stephen D. Bentley, Roland Brosch, Stephen V. Gordon, David A. Hopwood, and Stewart T. Cole
Parasite Genomics
Malcolm J. Gardner
Genome Sequence of an Extremely Halophilic Archaeon
Shiladitya DasSarma
Part VI: Applications of Genomic Data
Microarrays, Expression Analysis, and Bacterial Genomes
Carsten Rosenow and Brian Tjaden
Microbial Population Genomics and Ecology: A New Frontier
Edward F. Delong
Application of Genomics to Biocatalysis and Biodegradation
Lawrence P. Wackett
Enzyme Discovery and Microbial Genomics
Robert M. Kelly and Keith R. Shockley
Integration of Genomics in the Drug Discovery Process
Jacques Ravel
A Genomic Approach to Vaccine Development
Rino Rappuoli, Vega Masignani, Mariagrazia Pizza, Guido Grandi, and John L. Telford
Microbial Proteomics
Svend Birkelund, Brian B. Vandahl, Allan C. Shaw, and Gunna Christiansen
Index
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